Cholinergic and anti-cholinergic Flashcards
Which of the following drugs blocks the action of acetylcholine at muscarinic receptors?
A) Atropine
B) Nicotine
C) Donepezil
D) Physostigmine
A) Atropine
Cholinergic agonists primarily mimic the effects of:
A) Acetylcholine
B) Dopamine
C) Serotonin
D) Norepinephrine
A) Acetylcholine
Which of the following drugs is a reversible acetylcholinesterase inhibitor?
A) Atropine
B) Pralidoxime
C) Scopolamine
D) Tolterodine
B) Pralidoxime
Which of the following statements regarding cholinergic agonists is true?
A) They decrease gastrointestinal motility
B) They increase heart rate
C) They decrease bronchial secretions
D) They cause pupil constriction
Answer: D) They cause pupil constriction
The primary clinical use of atropine is:
A) To treat urinary retention
B) To treat Alzheimer’s disease
C) To treat bradycardia
D) To treat depression
Answer: C) To treat bradycardia
Which of the following is a common adverse effect of anticholinergic drugs?
A) Diarrhea
B) Bradycardia
C) Miosis
D) Dry mouth
Answer: D) Dry mouth
Which of the following is an example of a direct-acting cholinergic agonist?
A) Donepezil
B) Scopolamine
C) Neostigmine
D) Bethanechol
Answer: D) Bethanechol
The antidote for anticholinergic toxicity is:
A) Physostigmine
B) Atropine
C) Pralidoxime
D) Tolterodine
A) Physostigmine
Which of the following cholinergic agonists is used to treat myasthenia gravis?
A) Atropine
B) Neostigmine
C) Glycopyrrolate
D) Oxybutynin
B) Neostigmine
Which of the following drugs is a cholinergic agonist used in the treatment of xerostomia?
A) Atropine
B) Pilocarpine
C) Tolterodine
D) Physostigmine
B) Pilocarpine
Which of the following drugs is a cholinergic agonist used in the treatment of urinary retention?
A) Atropine
B) Neostigmine
C) Bethanechol
D) Scopolamine
C) Bethanechol
Which of the following drugs is a cholinesterase inhibitor used in the treatment of myasthenia gravis?
A) Ipratropium
B) Rivastigmine
C) Pyridostigmine
D) Tolterodine
Answer: C) Pyridostigmine
Which of the following cholinergic agonists is used in the treatment of Alzheimer’s disease?
A) Donepezil
B) Neostigmine
C) Atropine
D) Scopolamine
A) Donepezil
Which of the following drugs is a cholinesterase inhibitor used in the treatment of myasthenia gravis?
A) Ipratropium
B) Rivastigmine
C) Pyridostigmine
D) Tolterodine
C) Pyridostigmine
What are the major contraindications of direct cholinergic agonists
Asthma and peptic ulcers
What are some reversible indirect cholinergic agonist
Nicotine, neostigmine, physostigmine
What are some irreversible indirect cholinergic agonist
Sarin, malathion, parathion
What drug can be used to reverse the effect of non-depolarising NMBA?
Neostigmine- anticholinesterase
Which muscarinic receptor has a sympathetic cholinergic receptor ?
M3 in secretory glands (Eccrine glands)
What is the drug effect of bethanechol?
It decreases detrusor tone, and reduce outlet resistance of the internal sphincter, increase GI motility and secretion.
What are the side effects of varenicline?
May be associated with psychiatric symptoms such as suicidal ideation
What are the antidotes for organophosphates
Pralidoxime and atropine
What is the effect of parasympatholytics on the pupil of the eye?
Mydriasis ( dilation)
Because is parasympatholytic (anti cholinergic effect)
