CHOLINERGIC AGONIST AND ANTAGONIST (EXAM2) Flashcards
what is the main function of an cholinergic agonist drug
they stimulate the parasympathetic nervous system
what drug do cholinergic agonist mimic
acetylcholine
what are the 2 receptors for cholinergic receptors
muscarinic
nicotinic
what are the types of cholinergic agonist
direct acting
indirect acting
direct acting cholinergic
acts on receptors to activate tissue response
target specific sites
indirect acting cholinergic agonist
inhibit action of enzyme cholinesterase
the effect of cholinergic agonist on the cardiovascular system
-ITS ALL PAARSYMPATHETIC
-decrease BP, HR
-vasodilation
-slow conduction of the AV node
cholinergic agonist and GI
-increase muscle tone, motility, peristalsis, and relax muscle sphincter
-active bowel sounds
cholinergic agonist and GU
-Increase urine output
cholinergic agonist and eyes
constriction
cholinergic agonist and lungs
bronchial constriction
increase in secretion
with cholinergic agonist what kind of cough is there
productive cough from the increase in secretion
Indirect acting cholinergic function
they inhibit the cholinesterase enzyme
-allow acetylcholine to accumulate at receptor sites
Indirect acting cholinergic effects
-muscle contraction
-increased muscle tone
-bronchial constriction
-bradycardia
-miosis
-increased GI motility
-promote urination
Cholinergic antagonist
the stop the effects of acetylcholine by occupying the acetylcholine receptors
Anticholinergics and the heart
-large doses cause an increase HR
-small doses decrease HR
Anticholinergics and the lungs
-bronchodilation
-decrease secretion
Anticholinergics and GI
-relaxes the smooth muscle tone
-decrease motility
-decrease peristalsis and secretions
-CONSTIPATION
Anticholinergic effects
decrease secretion
less movement
constipation
Anticholinergic and the eye
dilate
decrease in accommodation
Anticholinergics and exocrine gland
dry mouth
decrease salvation and perspiration
Anticholinergic and CNS
decrease in tremors and rigidity of muscles
Since anticholinergics decrease tremors and rigidity of muscles what can it be given for
Parkinson disease
Atropine is an example of a what
anticholinergic
atropine action
increases heart rate
pupil dilation
decrease GI motility and gastric secretions
side effects of atropine (anticholinergic)
tachycardia
blurred vision
photophobia
what are some nursing intervention with a patient who is taking an anticholinergic
urinary retention
patient is fall risk because of decreased visual acuity
hypertension
SLUDGE
cholinergic
increase
Salvation
Lacrimation
Urinary incontinence
Diarrhea
Gastrointestinal cramps
Emesis
SLUDGE
anticholinergic
decrease
Salvation
Lacrimation
Urinary incontinence
Diarrhea
Gastrointestinal cramps
Emesis
