Chloroplasts, Apoptosis, Endomembrane (Transport) Flashcards
-Transport of material between compartments
-Organelle ↔ PM
- Organelle↔ Organelle
-Utilizes transport vesicles (~50-70nm)
-Small, spherical, membrane - enclosed organelles that bud off donor compartments and fuse with acceptors or recipient compartment
- Targeted movement (directed)
-Uses cytoskeleton and motor proteins
-Sorting signals recognized by receptors
Key elements of vesicle trafficking compartments (Step 1)
- Movement of vesicle - uses cytoskeleton and motor proteins (can be anterograde or retrograde)
Key elements of vesicle trafficking compartments (Step 2)
- Tethering vesicle to target compartment -via proteins from the Rab family of protein and other more specialized proteins
Key elements of vesicle trafficking compartments (Step 3)
- Docking vesicles to target compartments (uses proteins called snares)
Key elements of vesicle trafficking compartments (Step 4)
- Fusion of vesicle and membrane
Transport of transmembrane proteins
Orientation of transmembrane proteins with respect to the cytoplasm and the interior of membrane - bound compartments is maintained during its travel through the endomembrane system
Exocytosis
A vesicle from the inside of the moves into the cell surface, the vesicle membrane fuses with the cell membrane (restoring the membrane removed)
Endocytosis
When the cell membrane folds inwards trapping and enclosing small amounts of matter from the extracellular fluid
Pinocytosis
(A form of endocytosis)
- “cell drinking”
-The intake of a small droplet of extracellular fluid, together with any dissolved substance or very small particles that it may contain
Phagocytosis
(A form of endocytosis)
- Is the intake of a large droplet of ECF, often including particular matter such as bacteria or bits of organic material
Receptor-assisted endocytosis
-Involves the intake of specific molecules that attach to special proteins in the cell membrane that serve as receptors
-These membrane receptors passes a uniquely shaped projection or cavity that fits the shape of only one specific molecule