Chloramphenicol and some antibiotics points Flashcards
1
Q
What is the action of chloramphenicol ?
A
Inhibits peptidly transferase enzyme so stops bacteria being made
2
Q
What are the side effects of chloramphenicol ?
A
- Allergy
- Aplastic anaemia (deficiency of all 3 blood cell types)
- Grey baby syndrome
3
Q
What do you need to be careful about when giving steroids to treat keratitis ?
A
That you know its autoimmune cause rather the herpes as it can cause a corneal melt/perforation of the cornea
4
Q
What is the action of penicillins & cephalosporins ?
A
Inhibit cell wall synthesis through B lactam ==> kill bacteria
5
Q
What is the action of quinolones ?
A
Inhibit nucleic acid synthesis by inhibiting DNA gyrase ==> cell death
6
Q
What is the action of aciclovir ?
A
Inhibits viral DNA synthesis
