Chlamydia Rickettsia

Question 1

Obligate intracellular bacteria?

Answer 1

Chlamydia - most common STD
Rickettsia
Need ATP for cellular activity

Question 2

How is the chlamydial cell wall different?

Answer 2

No peptidoglycan layer

No muramic acid

Question 3

Two forms of chlamydia?

Answer 3

Elementary body - inactive but infectious, enters via endocytosis
Inclusion body - metabolically active, replicates intracellularly by fission

Question 4

Two habitats of chlamydia?

Answer 4

Eyes

Genital tract

Question 5

Most common cause of preventable blindness in the world?

Answer 5

Trachoma from Chlamydia

chronic keratoconjunctivitis, pull eyelid inward, lashes rub against conjunctivae

Question 6

Trachoma due to what serotypes of Chlamydia?

Answer 6

A B and C
Africa
Blindness
Chronic infection

Question 7

Oval cytoplasmic inclusions near the nuclei of conjunctival cells in trachoma?

Answer 7

Halberstadter Prowazek

Question 8

Chlamydia serotypes responsible for STD and neonatal pneumonia?

Answer 8

D to K

Question 9

Bacteria associated with reiter’s?

Answer 9

Chlamydia
Campylobacter
Can’t pee, see, climb a tree

Question 10

Characteristic cough in neonatal pneumonia by chlamydia?

Answer 10

Paroxysmal staccato cough

Late onset 2-4 weeks

Question 11

Chlamydia serotypes L1 L2 L3 cause what lesion?

Answer 11

LGV (Buboes)
Lymphogranuloma venereum
positive Frei test

Question 12

Treatment of chlamydia STD?

Answer 12

Ceftriaxone for neisseria

Doxycycline (nonpregnant) or Azith (pregnant)

Question 13

Also known as bird fancier’s disease?

Answer 13

Psittacosis
Caused by chlamydia psittaci
Parrots, parakeets

Question 14

DOC for chlamydial conjunctivitis?

Answer 14

Erythromycin

GI upset, hepatitis

Question 15

DOC for chlamydial LGV?

Answer 15

Doxycycline

Question 16

DOC for chlamydial psittacosis?

Answer 16

Azithromycin

Question 17

Cross reaction with proteus vulgaris strains to detect rickettsia?

Answer 17

Weil-Felix reaction

Question 18

Vector for rickettsia in rocky mountain spotted fever?

Answer 18

Tick (Dermacentor)

R. rickettsii

Question 19

Characteristic symptoms of RMSF?

Answer 19

Imagine MRS picture
Fever, conjunctival redness, headache, rash that starts in the palms, wrists then spread to trunk
Centripetal spread

Question 20

Vector for rickettsia in epidemic typhus?

Answer 20

Body louse
R. prowazekii
Centrifugal rash that spares palms soles and face vs RMSF (centripetal)

Question 21

Bacteria responsible for Q fever?

Answer 21

Coxiella burnetti

Question 22

Unique features of Q fever vs other rickettsial infections?

Answer 22

No vector, no rash
Negative weil-felix
Transmitted via inhaled endospore from cowhide

Question 23

Cat scratch disease?

Answer 23

Bartonella henselae

Question 24

Cause bacterial vaginosis?

Answer 24

Gardnerella vaginalis

Question 25

Test for bacterial vaginosis?

Answer 25

Whiff test
KOH - fishy odor
(+) clue cells

Question 26

Cause mesenteric adenitis or pseudoappendicitis?

Answer 26

Yersinia enterolitica

Question 27

Granuloma inguinale (Donovanosis)?

Answer 27

Klebsiella granulomatis

Question 28

Bacteria that look like safety pins?

Answer 28

Yersinia pestis

Klebsiella granulomatis

Question 29

Characteristic skin lesion in donovanosis?

Answer 29

Beefy red ulcer

Pseudobuboes