Chlamydia Rickettsia Flashcards

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1
Q

Obligate intracellular bacteria?

A

Chlamydia - most common STD
Rickettsia
Need ATP for cellular activity

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2
Q

How is the chlamydial cell wall different?

A

No peptidoglycan layer

No muramic acid

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3
Q

Two forms of chlamydia?

A

Elementary body - inactive but infectious, enters via endocytosis
Inclusion body - metabolically active, replicates intracellularly by fission

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4
Q

Two habitats of chlamydia?

A

Eyes

Genital tract

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5
Q

Most common cause of preventable blindness in the world?

A

Trachoma from Chlamydia

chronic keratoconjunctivitis, pull eyelid inward, lashes rub against conjunctivae

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6
Q

Trachoma due to what serotypes of Chlamydia?

A

A B and C
Africa
Blindness
Chronic infection

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7
Q

Oval cytoplasmic inclusions near the nuclei of conjunctival cells in trachoma?

A

Halberstadter Prowazek

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8
Q

Chlamydia serotypes responsible for STD and neonatal pneumonia?

A

D to K

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9
Q

Bacteria associated with reiter’s?

A

Chlamydia
Campylobacter
Can’t pee, see, climb a tree

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10
Q

Characteristic cough in neonatal pneumonia by chlamydia?

A

Paroxysmal staccato cough

Late onset 2-4 weeks

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11
Q

Chlamydia serotypes L1 L2 L3 cause what lesion?

A

LGV (Buboes)
Lymphogranuloma venereum
positive Frei test

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12
Q

Treatment of chlamydia STD?

A

Ceftriaxone for neisseria

Doxycycline (nonpregnant) or Azith (pregnant)

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13
Q

Also known as bird fancier’s disease?

A

Psittacosis
Caused by chlamydia psittaci
Parrots, parakeets

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14
Q

DOC for chlamydial conjunctivitis?

A

Erythromycin

GI upset, hepatitis

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15
Q

DOC for chlamydial LGV?

A

Doxycycline

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16
Q

DOC for chlamydial psittacosis?

A

Azithromycin

17
Q

Cross reaction with proteus vulgaris strains to detect rickettsia?

A

Weil-Felix reaction

18
Q

Vector for rickettsia in rocky mountain spotted fever?

A

Tick (Dermacentor)

R. rickettsii

19
Q

Characteristic symptoms of RMSF?

A

Imagine MRS picture
Fever, conjunctival redness, headache, rash that starts in the palms, wrists then spread to trunk
Centripetal spread

20
Q

Vector for rickettsia in epidemic typhus?

A

Body louse
R. prowazekii
Centrifugal rash that spares palms soles and face vs RMSF (centripetal)

21
Q

Bacteria responsible for Q fever?

A

Coxiella burnetti

22
Q

Unique features of Q fever vs other rickettsial infections?

A

No vector, no rash
Negative weil-felix
Transmitted via inhaled endospore from cowhide

23
Q

Cat scratch disease?

A

Bartonella henselae

24
Q

Cause bacterial vaginosis?

A

Gardnerella vaginalis

25
Q

Test for bacterial vaginosis?

A

Whiff test
KOH - fishy odor
(+) clue cells

26
Q

Cause mesenteric adenitis or pseudoappendicitis?

A

Yersinia enterolitica

27
Q

Granuloma inguinale (Donovanosis)?

A

Klebsiella granulomatis

28
Q

Bacteria that look like safety pins?

A

Yersinia pestis

Klebsiella granulomatis

29
Q

Characteristic skin lesion in donovanosis?

A

Beefy red ulcer

Pseudobuboes