Chlamydia Rickettsia Flashcards
Obligate intracellular bacteria?
Chlamydia - most common STD
Rickettsia
Need ATP for cellular activity
How is the chlamydial cell wall different?
No peptidoglycan layer
No muramic acid
Two forms of chlamydia?
Elementary body - inactive but infectious, enters via endocytosis
Inclusion body - metabolically active, replicates intracellularly by fission
Two habitats of chlamydia?
Eyes
Genital tract
Most common cause of preventable blindness in the world?
Trachoma from Chlamydia
chronic keratoconjunctivitis, pull eyelid inward, lashes rub against conjunctivae
Trachoma due to what serotypes of Chlamydia?
A B and C
Africa
Blindness
Chronic infection
Oval cytoplasmic inclusions near the nuclei of conjunctival cells in trachoma?
Halberstadter Prowazek
Chlamydia serotypes responsible for STD and neonatal pneumonia?
D to K
Bacteria associated with reiter’s?
Chlamydia
Campylobacter
Can’t pee, see, climb a tree
Characteristic cough in neonatal pneumonia by chlamydia?
Paroxysmal staccato cough
Late onset 2-4 weeks
Chlamydia serotypes L1 L2 L3 cause what lesion?
LGV (Buboes)
Lymphogranuloma venereum
positive Frei test
Treatment of chlamydia STD?
Ceftriaxone for neisseria
Doxycycline (nonpregnant) or Azith (pregnant)
Also known as bird fancier’s disease?
Psittacosis
Caused by chlamydia psittaci
Parrots, parakeets
DOC for chlamydial conjunctivitis?
Erythromycin
GI upset, hepatitis
DOC for chlamydial LGV?
Doxycycline