childhood/dolescent infections Flashcards
red flags for childhood infx: persistent pain swelling/redness in 1 joint fever unusual rash 6 more
loss of appetite fever limp weakness unexplained weight loss tired
5 MC ped cancers
- leukemia
- cns tumor
- lymphoma (hodgkins, non >15y)
- bone cancer
- neuroblastoma (infants)
2 MC childhood bone cancers
ewing’s sarcoma
osteogenic sarcoma
MC solid tumor besides CNS tumor, 50% dx’d in first 2 years
neuroblastoma
- abx resistant infx if in marrow, stiff neck, HA, vomit, bone pn
- if hypothalamus destroying, inc appetite and weight
leukemia
cancer in 5-10yo, often mis dx’d dt rapid growth and mimic of other dx
CNS/brain tumor
B and T cell, burkett’s lymphoma
painless swelling, often liver and spleen
non-hodgekin’s lymphoma
rare cancer male 2:1 involving the long bones around the knee
bone cancer
osteosarc >ewings
cancer usually in adrenal glands, abd, neck, pelvic or chest sympathetic ganglia
neuroblastoma
s/s: swollen gums, fever, pallor, bleeding, bone pain, fatigue
leukemia
s/s: HA worse in AM, n/v, seizure, personality change, ataxia, hemiplegia, blurry vision, CN palsies
CNS/brain tumor
s/s cells spreadin lymph glands of neck, chest, abd
fatigue, fever, cough, chills, night sweats, pruritis, HA, weight loss, facial edema, abd pn, SOB
lymphoma
non and hodgkins
s/s pain and swelling at site of tumor, pain progresses to severe, limp, wakes at night with fever and sweating, systemic signs of infx
bone cancer
s/s: fever, abd pn, weight loss, FTT, irritability, abd or c/s mass, chronic/watery diarrhea, ptosis, pallor, croup, bowel/bladder dysfx
neuroblastoma
CHILDCANCER acronym
Continued, unexplained weight loss HA, with early AM vomiting Inc swelling/bone pn Lump/mass Dev of bruising/bleeding/rash Constant infx A whitish color behind eye Nausea or vomiting Constant tireness/pallor Eye/vision changes Recurrent fever of unknown origin
hard, non-mobile/non-tender lymph nodes unexplained weight loss abd mass (+ blood) recurrent HAs cervical lymphadenopathy unexplained weight loss occult blood in stool/urine bone pain (esp w fever)
childhood cancer red flags
MC malignancy in children
ALL
leukemia with lower cure rate, 15%
AML
HA, visual disturbances, general discomfort in extremities could indicate a ____ tumor
pituitary
16x22mm (acrossxdeep) on xray taken at 40” FFD is indicative of
enlarged sella turcica
pituitary adenoma secreting growth hormone
acromegaly
gigantism
onset of growth hormone oversecretion of this disorder occurs prior to skeletal maturation (open physis)
gigantism