Chemotherapeutic Agents

Question 1

It is the prevention or treatment of disease by the use of chemical substances

Answer 1

Chemotherapy

Question 2

chemically treating an ailment

Answer 2

Chemotherapy

Question 3

This refers to the synthetic chemical

Answer 3

Chemotherapeutic agents

Question 4

A generic term referring to either antibiotics or chemotherapeutic agents

Answer 4

antimicrobic or antimicrobial agents

Question 5

this is a term used to describe all types of antimicrobial agents

Answer 5

antibiotic

Question 6

This is the ability of a drug to target sites that are relatively specific to the microorganism

Answer 6

selective toxicity

Question 7

This is a requirement for effective and safe chemotherapy of infections caused by invading organisms

Answer 7

selective toxicity

Question 8

this is a unique characteristic of antibiotic agents

Answer 8

Selective toxicity

Question 9

Example of target sites unique to the microorganism

Answer 9

Bacterial cell wall synthesizing enzyme
bacterial ribosomal
the molecular machinery of viral replication

Question 10

Results of selective toxicity

Answer 10

• Accumulation of drug to higher levels of microorganism than in human cells
• a specific action of a drug on cellular structures that are unique to the microorganism
• actions of drugs on biochemical processes that are more critical to the parasite than to the host

Question 11

True or False

high selectivity of antibiotics are normally toxic

Answer 11

False

Question 12

This type of drug is capable of inhibiting the reproduction of the microorganism but does not kill it

Answer 12

Bacteriostatic

Question 13

True or False

Bactericidal are reversible upon removal

Answer 13

False

bacteriostatic is the type of drug that will be reversible upon removal

Question 14

Example of drugs that have a bacteriostatic characteristic

Answer 14

erythromycin, sulfonamide, and tetracyclines

Question 15

this type of drug is dependent on the defense mechanism of the host

Answer 15

Bacteriostatic

Question 16

This type of drug actively kills the bacteria

Answer 16

Bactericidal

Question 17

Types of bactericidal

Answer 17

beta-lactam antibiotics and aminoglycosides

Question 18

This type of drug is less dependent on the defense mechanism of the host for their therapeutic action

Answer 18

Bactericidal

Question 19

For the treatment of the endocardium and meningitis, what type of drug is more preferred

Answer 19

bactericidal

Question 20

why is bactericidal preferred in endocardium and meningitis

Answer 20

because the host defenses in this area are relatively ineffective

Question 21

This is a common practice used to treat tuberculosis

Answer 21

Combination therapy

Question 22

Bacterial cell walls are formed via?

Answer 22

Biosynthetic pathways

Question 23

Drugs that inhibit bacterial cell wall synthesis by inhibiting the synthesis of precursors of murein

Answer 23

Cytosine and vancomycin