Antidepressants

Question 1

depression is a result of

Answer 1

deficiency of

serotonin
norepinephrine
dopamine

Question 2

Monoamine depletion could cause

Answer 2

postsynaptic receptor to upregulate

Question 3

Serotonin producing neuron is

Answer 3

presynaptic serotonergic

Question 4

norepinephrine producing neuron is a

Answer 4

noradrenergic neuron

Question 5

Serotonin is synthesized from

Answer 5

amino acid tryptophan

Question 6

Norepinephrine is synthesized from

Answer 6

amino acid tyrosine

Question 7

This inhibits the reuptake of serotonin blocking the serotonin transporter

Answer 7

Selective serotonin reuptake inhibitor

Question 8

The increase of norepinephrine and serotonin levels is a result of?

Answer 8

blocking of norepinephrine transporter by SNRI’s

Question 9

This is named after the core chemical structure which contains 3 rings connected together

Answer 9

tricyclic antidepressants

Question 10

This is more selective to norepinephrine

Answer 10

desipramine

Question 11

the mitochondrial enzyme that degrades monoamines

Answer 11

monoamine oxidase inhibitors

Question 12

This metabolizes serotonin, norepineprhine and dopamine

Answer 12

MAO subtype a

Question 13

MAO subtype B metabolizes

Answer 13

dopamine