Chemical/Biological/Nuclear/Radiological warfare Flashcards
Schedule 1 chemical agents are used how
few legitimate uses
Schedule 2 chemical agents are used how
small scale use
Schedule 3 chemical agents are used how
large scale industrial uses
Name three blistering agents
Mustard
Lewisite
Phosgene oxime
The chemical agent mustarg smells like
Garlic, onions, mustard, or odorless
How to treat mustard exposure
give milk
*don’t induce vomiting
Mustard has what effect on eyes
blindess up to 10 days
Lewisite smells like
geraniums (flowers)
Lewisite contains
arsenic
Lewisite may cause
hypotension
Phosgene oxime causes skin to have
red ring hives
Phosgene oxime causes what respiratory effect
pulmonary edema
Phosgene oxime should be treated with
water (flush 5-10 minutes)
Name five blood agents that affect the body by inhibiting the use and transfer of oxygen
Arsine Cyanide Hydrogen Cyanide Cyanogen Chloride Sodium/Potassium cyanide
Cyanide smells like
bitter almond or no scent at all
What is the MOA of cyanide poisoning
cyanide ions halts cellular respiration by inhibiting cytochrome C oxidase preventing cells from ultilizing oxygen
What are CV signs of cyanide toxicity
brady and HTN»hypotension with Tachycardia»brady and Hypotension
*expect falsely elevated pulse oximetry
What skin color is noted in someone with cyanide toxicity
cherry red
What three drugs are used to tx cyanide toxicity
Amyl nitrate
Sodium nitrite
Sodium thiosulfate
Arsine causes damage to
RBC
Arsine has what odor
garlic
Arsine is spread through
air
Name two Choking agents
Chlorine
Phosgene
*cause pulmonary edema and respiratory failure
What does chlorine smell like
bleach
Phosgene smells like
hay, green corn
How long could it take for phosgene symptoms to occur
48 hours
Two classes of nerve agents include
carbamates
organophosphates
what are three carbamates
physostigmine, neostigmine, and pyridostigmine
What is an example of organophospates
irreversible pesticides
G-series nerve gases include
Tabun
Sarin
Soman
V-series nerve gases include
VX
Nerve agents work by
inhibiting cholinesterase»respiratory paralysis
What are early symptoms of nerve agent toxicity
Muscarinic effects
bronchospasm, bradycardia, miosis, SLUDGE
What are late symptoms of nerve agent toxicity
Nicotinic effects
Motor»flaccid paralysis>apnea>death
What are three antidotes to nerve agent toxicity
Atropine
2-PAM
Benzodiazepines
If antidotes for nerve agent given too quickly, what can happen
Resp/cardiac arrest
What agent is given as a prophalactic to nerve agent exposure
pyridostigmine
Treatment of nerve gas with atropine can lead to Central anticholineric syndrome which manifests how?
hyperthermia (from impaired sweating) dry mouth flushed skin (red) mydriasis delirium
What is the antidote of atropine
physostigmine
Name four biologic conditions that cause injury in warfare
anthrax
variola
viral hemorrhagic fever
plague
Is inhalational anthrax infectious
no
*patient goes thru period of improvement»>sudden severe symptoms
Small pox is caused by a virus and is characterized by
lung infection»bloodstream»to surface»RASH
Ebola is known as
Viral hemorrhagic fever
Name three toxins
Ricin
Botulism
Saxitorxin
What is the most deadly toxin known
Botulism
Botulism works by
binding to presynaptic cholinergic receptors»>decreaed Ach
*flaccid paralysis
Saxitoxin effects
sodium channels via blockage
*death within minutes with inhalation