Chedy - theme 6 Flashcards
Giant squid giant axons:
0.5mm diameter. Unmyelinated, which decreases conduction velocity. Voltmeter records voltage difference between inside/outside of neuron.
Resting potential inside cells:
-70 mV. Interior is more negative.
Membrane factors that contribute to RESTING potential:
Na+/K+ ATPase pump, ion channels, negatively charged ions
Na+/K+ ATPase pump:
Transports 3 Na+ out and 2 Ka+ in.
The stronger the stimulus, the stronger the response?
NO!
Potassium channels : sodium channels. Significance?
50x more K+ than Na+. At rest, the membrane is more permeable to K+.
Evolution of the Na+/K+ pump:
K+ opens one ms later than Na+. Na+ goes out really fast, then K+ comes in to fix the charge.
Saltatory conduction of action potentials:
Signals travel super fast because myelination only allows charge conduction in certain places. There’s a diagram for this.
Summation:
EPSPs hang out for a bit and then they add up (constructive interference). Then they calm the frick down and cancel out with IPSPs.
Graded potentials:
Excitatory postsynaptic potentials and inhibitory postsynaptic potentials are summed