chapter twenty two (sex differences)

Question 1

what does the dopamine hypothesis of schizophrenia theorize

Answer 1

overactive dopaminergic system, D2 receptors blocked helps

Question 2

what does the glutamate hypothesis of schizophrenia theorize

Answer 2

underactive NMDA receptor, may affect both glutamatergic and GABAergic function

Question 3

classic antipsychotics are ___ receptor antagonists, effective against positive symptoms; side affects: ______ effects

Answer 3

D2, parkinsons

Question 4

atypical (new generation) antipsychotics - ____ and _____ antagonists, effective against posiitve and negative symptoms; side affects: weight gain, type II diabetes, decreased motor side affects

Answer 4

D2 & 5-HT

Question 5

glycine is a co-agonist of _____ with glutamate

Answer 5

NMDAR

Question 6

_____ have greater prevalence of anxiety disorders and depression

Answer 6

females

Question 7

_____ have greater prevalence of alcohol and drug dependence

Answer 7

males

Question 8

____ makes neurons more active

Answer 8

estrogen