Chapter 9.1 - Glycolysis

Question 1

Glycolysis

Answer 1

Glucose splits into 3 carbon sugars, which are oxidized and their remaining atoms rearranged to form two molecules of pyruvate.

Question 2

Investment Phase

Answer 2

Spends energy (2ATP)

Question 3

Payoff Phase

Answer 3

ATP is produced by substrate level phosphorylation and NAD+ is reduced to NADH by electrons released from the oxidation of glucose.

Question 4

Net Energy Yield of Glycolysis

Answer 4

• 2 ATP
• 2 NADH
• 2 Pyruvate

Question 5

Is glycolysis anaerobic or aerobic?

Answer 5

Either: it will occur whether or not O2 is present

Question 6

If O2 is present in Glycolysis, what is possible?

Answer 6

The TCA Cycle can function and the chemical energy stored in pyruvate and NADH can be extracted.

Question 7

Where does glycolysis occur?

Answer 7

In the cytoplasm

Question 8

Unstable ATP is hydrolisized into what?

Answer 8

ADP + Pi (more stable)

Question 9

ATP/ADP Structure

Answer 9

Adenine, 5C sugars and 3 Pi

Question 10

Why is ATP considered high energy?

Answer 10

• PO43 is very negative
• Cleave one P
• Releases a lot of energy since the negative forces repel

Question 11

NADH/NAD+ is an

Answer 11

Electron carrier

Question 12

Glycolysis is what kind of phosphorylation?

Answer 12

Substrate level

Question 13

Pyruvate is oxidized into:

Answer 13

Acetate + CoA (enzyme lost CO2)

Question 14

What’s the first thing in the TCA Cycle?

Answer 14

The acetyl CoA from pyruvate

Question 15

Is the TCA Cycle aerobic or anaerobic?

Answer 15

Aerobic: oxygen is present

Question 16

Where does the TCA Cycle occur? How does pyruvate get there?

Answer 16

• Cytosol of the Mitochondria

- Pyruvate gets there via active transport (since it’s charged) with the help of a transport protein

Question 17

Products of TCA Cycle

Answer 17

• a LOT of NADH
• a little FADH2
• NOT a lot of energy, but carries lots of electrons

Question 18

What is lost from pyruvate to acetyl CoA?

Answer 18

CO2 is lost from breaking pyruvate’s carboxyl group, as well as NADH and H+

Question 19

The reaction of acetyl CoA to yield lower energy products is

Answer 19

Exergonic

Question 20

What kind of phosphorylation is the TCA Cycle

Answer 20

Substrate level

Question 21

What are the products of TCA from 2 pyruvate (1 glucose)?

Answer 21

• 8 NADH
• 2 FADH2
• 2 ATP
• 3 CO2