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My Packs: (WIZEPREP) (BIOCHEM 2280) > Chapter 9: 9.1 Glycolysis > Flashcards

Chapter 9: 9.1 Glycolysis Flashcards

1
Q

When ————— levels are low ATP must be produced

A

Phosphocreatinine

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2
Q

What transports glucose into the cytoplasm where glycolysis occurs?

A

GLUT 4

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3
Q

In glycolysis:

What happens to glucose?

A

Converted to 2 pyruvate molecules
* NET gain of 2 ATP and 2 NADH molecules

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4
Q

Steps of Glycolysis:

Step 1 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. Glucose
  2. Glucose-6-Phosphate
  3. Hexokinase

(1 ATP consumed)

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5
Q

Steps of Glycolysis:

Step 2 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. Glucose-6-Phosphate
  2. Fructose-6-Phosphate
  3. Phosphoglucose isomerase
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6
Q

Steps of Glycolysis:

Step 3 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. Fructose-6-Phosphate
  2. Fructose-1,6-Biphosphate
  3. Phosphofructokinase-1

(1 ATP consumed)

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7
Q

Steps of Glycolysis:

Step 4 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. β-D-Fructose-1,6-Biphosphate
  2. D-Glyceraldehyde-3-Phosphate + Dihydroxyacetone Phosphate
  3. Aldolase
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8
Q

Steps of Glycolysis:

Step 5 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. Dihydroxyacetone Phosphate
  2. D-Glyceraldehyde-3-Phosphate
  3. Triose Phosphate Isomerase
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9
Q

Steps of Glycolysis:

Step 6 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. D-Glyceraldehyde-3-Phosphate
  2. D-1,3-Biphosphoglycerate
  3. Glyceraldehyde-3-Phosphate Dehydrogenase

(2 NADH produced)

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10
Q

Steps of Glycolysis:

Step 7 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. D-1,3-Biphosphoglycerate
  2. 3-Phosphoglycerate
  3. Phosphoglycerate Kinase

(2 ATP produced)

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11
Q

Steps of Glycolysis:

Step 8 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. 3-Phosphoglycerate
  2. 2-Phosphoglycerate
  3. Phosphoglycerate Mutase
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12
Q

Steps of Glycolysis:

Step 9 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. 2-Phosphoglycerate
  2. Phosphoenolpyruvate
  3. Enolase
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13
Q

Steps of Glycolysis:

Step 10 of Glycolysis:
1. Reactant
2. Product
3. Enzyme that catalyzes the reaction

(State ATP/NADH that is produced/consumed)

A
  1. Phosphoenolpyruvate
  2. Pyruvate
  3. Pyruvate Kinase

(2 ATP produced)

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14
Q

State:

ATP and NADH production/consumption in Glycolysis

A
  • Step 1: 1 ATP consumed
  • Step 3: 1 ATP consumed
  • Step 6: 2 NADH produced
  • Step 7: 2 ATP produced
  • Step 10: 2 ATP produced
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15
Q

How many steps are regulated in glycolysis? What do they have in common?

A

3 steps
* All have a large free energy change

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16
Q

Besides the 3 steps that are regulated, how else is glycolysis regulated?

A

Regulated by glucose

17
Q

Define:

Allosteric regulation

A

Regulation through bringing an effector molecule to a site other than the active site

18
Q

Which steps are regulated in glycolysis?

A
  • Step 1: Hexokinase
  • Step 3: PFK-1
  • Step 10: Pyruvate kinase
19
Q

In glycolysis:

How is Step 1 regulated?

A

Inhibited by:
* High product concentration

20
Q

In glycolysis:

How is Step 3 regulated?

A

Inhibited by:
* Large amount of ATP

Activated by:
* Large amounts of AMP
* Large amounts of product

21
Q

In glycolysis:

How is Step 10 regulated?

A

Inhibited by:
* Through phosphorylation
* ATP, alanine, and acetyl-CoA

Activated by:
* AMP and fructose-1,6-biphosphate

My Packs: (WIZEPREP) (BIOCHEM 2280) (32 decks)

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