Chapter 9 Flashcards
Define genetic mutation
A change in base sequence of chromosomes
What are mutagenic agents? - give 2 examples
Agents that increase the amount of genetic mutation that occurs
Carcinogens
Radiation
What are the 2 types of gene mutation?
Deletion
Substitution
Why might a gene mutation not affect a protein?
Because the genetic code is degenerate a substitution might not cause a change in amino acid because some amino acids are coded for by more than 1 triplet so it is possible the amino acid will remain the same
Define chromosome mutations
Changes in the structure or number of whole chromosomes
What is Polyploidy?
A condition in which organsims have 3 or more whole sets of chromosomes rather than 2
What is non disjunction?
A conditional where there is a change in the number of individual chromosomes where gametes have 1 more or less chromosomes than they should and therefore the cells have 1 more or less chromosomes than they should
Define substitution
A type of gene mutation in which a nucleotide in a DNA molecule is replaced by another nucleotide thay has a different base
Define deletion
A generic mutation that occurs when a nucleotide is lost from the normal sequence of DNA
Why does deletion cause such an impact?
Because all triplets following the deletion will be impacted because the sequence of bases is read in groups of 3 bases
What is meiosis used to make?
Gametes only
Are cells made by meiosis haploid or diploid?
Haploid
How many daughter cells are produced by meiosis?
4
Does meiosis make genetically identical or genetically diverse cells?
Genetically diverse
Meiosis can be described as a source of
Variation
What stages are involved in meioisis?
Replication of genetic information in interphase Prophase 1 Metaphase 1 Anaphase 1 Telophase 1 Prophase 2 Metaphase 2 Anaphase 2 Telophase 2
What happens in prophase 1?
Chromosomes condense and are seen as 2 chromatids
The maternal and paternal chromosomes come together to form a homologous pair
Crossing over occurs
The nucleolus disappears and the nuclear envelope breaks down
What happens in metaphase 1?
The homologous pairs of chromosomes line up on the equator of the spindle
Independent segregation is set up
What happens in anaphase 1?
Independent segregation occues
The homologous chromosomes (1 from each bivalent) separate to each pole
Each pole receives a haploid number of chromosomes (2cells)