Chapter 8 book notes Flashcards
Vitamins
-potent, essential, non-kcaloric, organic nutrients needed from foods in trace amounts.
-help perform functions that promote growth, reproduction, and maintience of health and life.
How to vitamins differ from carbs, fats, & proteins?
-structure: vitamins are individual units, they are not linked together.
-function: do not yield energy, but assist enzymes in release of energy.
-dietary intakes: vitamins are consumed in micrograms or milligrams, this is why they are known as micronutrients.
The only disease a vitamin will cure is the one…
-caused by a deficiency of that vitamin.
Vitamin A deficiency can cause=
Lack of naicin can cause=
Lack of vitamin D can cause=
-blindness
-dementia
-impede bone growth
Are vitamin supplements as good as vitamin rich foods?
-NO; vitamin supplements do not offer the many benefits that come from vitamin rich foods.
What 2 vitamins fall below recommended intakes?
-vitamin D
-folic acid (pregnant women)
Fat soluble vitamins:
-Vitamin A, D, E, & K
Water soluble vitamins:
B vitamins: thiamin, riboflavin, niacin, pantothenic acid, Biotin, Vitamin B6, folate, Vitamin B12, & vitamin C.
Amount of vitamins available from food depends on two factors:
1)quantity provided by a food
2)amount absorbed & used by body (bioavailability)
bioavailability
the rate and extent to which a nutrient is absorbed and used.
Determining bioavailability depends on these factors:
-efficiency of digestion & time of transit through GI tract
-previous nutrient intake & nutrition status
-other foods consumed at same time
-method of food preparation (raw or cooked)
-source of nutrient (natural, synthetic, or fortified).
Precursors
-vitamins available from foods in inactive forms known as precursors, (provitamins)
-once inside body, precursor is converted to the active form of vitamin
So when measuring a person’s vitamin intake it is important to count both the actual amount of a vitamin and ..
-potential amount available from its precursors.
Because vitamins are organic compounds..
-they can be readily destroyed during processing.
-so processed foods should be handled with care during storage and in cooking.
How can these vitamins be destroyed?
Thiamin=
Riboflavin=
Vitamin C=
-prolonged heating
-can be destroyed by UV rays of sun or fluorescent lights, so if stored in transparent glass, vitamin will be destroyed.
-oxygen destroys vitamin C so losses occur when food is cut, processed, and stored.
How minimize nutrient losses of vitamins:
-prevent enzymatic destruction; refrigerate most fruit, veggies, and jucies to slow down breakdown.
-protect from light & air
-prevent heat destruction or losses in water
Fat soluble vitamins
-Vitamin A,D,E, &K
-body absorbs them the same way as it absorbs lipids
-once absorbed they are stored in the liver & fatty tissues until body needs them.
-can build up to toxic conditions
What is the first fat-soluble vitamin to be recognized?
-Vitamin A and its precursor beta-carotene.
Roles of vitamin A:
-VERSATILE VITAMIN!!!
-gene expression, vision, cell differentiation, immunity, & reproduction & growth
3 active forms of vitamin A in the body:
1)Retinol: supports reproduction and is major storage and transport form of vitamin
2)Retinal: active in vision
3)Retinoic acid: acts as a hormone, regulating cell differentiation, growth and embryonic reproduction
Retinol is converted by cells to make?
-retinoic acid or retinal as needed
retinol-binding protein
-a special transport protein
-picks up retinol from liver, where it is stored, and carries it in the blood.
Vitamin A in gene expression
-hundreds of genes are regulated by retinoic acid.
-may affect the development & treatment of certain cancers
Vitamin A plays two roles in the eye:
-it helps maintain a healthy, crystal clear outer window (cornea)
-helps in light detection at the retina
When vitamin A is lacking what happens to the eye?
-the eye has difficulty adapting to changing light levels
Night blindness
-symptom of vitamin A deficiency
-at night, after eye has adapted to darkness, a flash of bright light is followed by a brief delay before eye can see again.
Vitamin A in protein synthesis and cell differentiation
-present in the skin and linings of organs to promote protein synthesis and cell differentiation.
cell differentiation
-process that allows each type of cell to mature so that it is capable of performing a specific function.
Epithelial tissue linings found in body
-skin
-covers the cornea
-lining of eyelids & sinus passageways.
-linings of mouth, stomach, intestines, lungs, and passages leading to them,
-lining of bladder, uterus, vagina
What substance does epithelial cells secrete to coat the tissues and protect them from invasive microorganisms?
-mucus
Vitamin A helps to maintain the integrity of what in cell differentiation?
-epithelial cells
Vitamin As role in immunity
-“anti-infective” vitamin
-help regulate genes involved in immunity
Vitamin A role in reproduction, growth, & development:
-IN women=
-in men=
-during pregnancy=
-in men it helps with sperm development
-in women it promotes fetal growth & development
-in pregnancy vitamin A is transferred to fetus and is essential in development of nervous system, lungs, kidneys, skeleton, eyes, & ears.
Besides being a precursor of Vitamin A, what other role does beta-carotene play?
-antioxidant; a compound that protects other compounds from attack by oxygen.
What can too much oxygen trigger in the body? (cell wise)
-free radicals
-start chain reactions in cell membranes that damage cell structures and impair cell functions
Oxidative and free radical damage can lead to what?
-early stages of cancer & heart disease
-age related blindness, Alzheimer’s, arthritis, cataracts, diabetes, and kidney disease.
Besides beta-carotene, what else is considered a dietary antioxidants?
-Vitamin E, C, mineral selenium, and many phytochemicals.
Has there been a recommended intake value for beta-carotene established by the DRI?
-NO
How much vitamin A can be stored in the body & where?
-up to a years supply
-90% stored in the liver
Deficiency symptoms of vitamin A would not begin to appear until?
-1-2 years
What is impaired in vitamin A deficiency?
-cell differentiation & maturation
Vitamin A deficiency & its affect in the eye
-process leads to drying and hardening of the cornea , which may progress to permanent blindness, also known as XEROPTHALMIA.
What is the major cause of preventable blindness in children worldwide?
-vitamin a deficiency causing half a million of children to lose their eyesight every year.
Stages of xerophthalmia:
-cornea becomes dry and hard because of lack of mucus production (xerosis)
-xerosis then becomes keratomalacia, the softening of the cornea that leads to irreversible blindness.
Vitamin A deficiency and how it affects the skin:
-epithelial cells flatten and begin to produce keratin (hard, inflexible protein of hair & nails).
-makes skin dry, rough, scaly, & hard.
Keratinization
-accumulation of keratin that makes a lump around each hair follicle.
Vitamin A and how it affects the mouth:
-results in drying & hardening of salivary glands, making them susceptible to infection.
Vitamin A deficiency and its affect in stomach & intestines lining:
-secretions of mucus in stomach and intestines are reduces, hindering normal digestion & absorption of nutrients.
Vitamin A deficiency and bodys defensive barriers
-makes a person more susceptiable to infections
-EX- measles kills 384 children each day, due to diarrhea and pneumonia, large doses of Vitamin A can reduce the risk of dying from these infections
What concentrated amounts of preformed vitamin A (active form of vitamin) foods can lead to vitamin A toxicity?
-foods derived from animals, fortified foods, or supplements
-PLANTS ONLY CONTAIN BETA-CAROTENE, AND DOES NOT CONVERT VITAMIN A RAPID ENOUGH TO CAUSE TOXICITY.
Overdoses (toxic levels) of vitamin a damage the same body systems & exhibit symptoms like that in?
-vitamin a deficiency
Who is most vulnerable to vitamin A toxictiy?
-children
What foods that children eat contain 100% or more of the recommended daily intake of vitamin A?
-breakfast cereals, instant meals, fortified milk, and chewabale candy like vitamins.
RDA recommendation for daily vitamin A intake for men and women:
- men= 900 micrograms
-women=700 micrograms
Excessive vitamin A can also pose a teratogenic risk, which is..?
-an abnormal fetal development and birth defects.
-too much vitamin A during pregnancy injure the spinal cord and other tissues of developing fetus
UL (tolerable upper intake level) for women of childbearing age
-3000 micrograms
How much of vitamin A do multivitamins supplements typically provide?
-1500 micrograms, which is more than people need
Vitamin A prescription and acne
-directly applied to skin surface, will help relieve acne symptoms but not cure acne.
Beta-carotene is measured not by micrograms but by?
-retinol activity equivalents (RAE), which expresses the amount of retinol the body actually derives from a plant after conversion
one microgram of retinol counts as 1 RAE, as well as ?micrograms of dietary beta-carotene?
-12
Overconsumption of beta carotene is never hazardous but it can do what to the skin?
-turn it bright yellow; this is because beta-carotene builds up in fat just beneath the skin and imparts a yellowish cast to the skin.
Overconsumption of beta-carotene supplements can be..
-harmful, especially to smokers.
Preformed (active form) vitamin A is found only in what kinds of food?
-foods of animal origin
Foods richest in vitamin A are:
-liver and fish oil, but milk, cheese, eggs, and butter and fortified cereals are also good sources.
Because vitamin A is fat soluble is it lost in milk when it is..
-skimmed, so milk that is fat free, reduced fat, or low fat have vitamin A
Margarine provides same amount of vitamin A as ?
-butter
Additional vitamin A rich foods:
-cooked spinach and carrots, baked sweet potato, cooked bok choy, and apricots
Beta carotene rich foods
-many foods from plants contain beta-carotene, which help give them their color
-orange pigments of fruit & veggies & dark green veggies
Bright orange veggies rich in beta carotene:
-carrots, sweet potatoes, pumpkins, cantaloupe, and apricots.
Dark green veggies rich in beta cartoene:
-spinach, broccoli
Vitamin D is different from the other nutrients in the body because…
-it can synthesize significant quantities with the help of sunlight.
-it is not a essential nutrient, with enough sun people do not need vitamin D from food