Chapter 8 Flashcards
Positive growth factors/regulators encourage _______.
mitosis
Negative growth factors discourage mitosis and may encourage _____ _____.
cell death
External growth factors tend to be hormones.
True
Hormones can act as either _______ or _______ growth regulators depending on the tissue and depending on the time.
positive or negative
The positive growth regulators can be compared to the gas pedal in a car.
True
Genes that encourage cell division and are necessary to normal development are called what?
Proto-Oncogenes
Oncogenes are proto-oncogenes that have abnormal expression.
True
Negative growth regulators are compared to the brake pedal on a car.
ture
Genes that prevent the cell cycle from continuing are called what?
Tumor Suppressor Genes
The gene ____ plays a vital role in maintain appropriate cellular division.
p53
More than half of all cancers indicated a loss of p53 activity in tumor cells.
True
Cancer develops because of one mutation in a single cell.
False, it is in multiple mutations accumulated.
Most human cancers are hereditary.
False, cancers are not hereditary
About 5% of cancers are results of inherited gene mutations.
True
___________ are physical, chemical, or biological agents that cause cancer.
Carcinogens
