Chapter 7 Powerpoint

Question 1

Microarray

Answer 1

Tool to detect levels of gene expression. When gene expressed it generates specific protein when silenced no proteins

Question 2

What causes unregulated cell divisions

Answer 2

Accumulated mutations in

Porto-oncogenes: signal cell to progress through cell cycle at appropriate time … overstimulate if mutated

Question 3

Tumor suppressor genes

Answer 3

Signal cells to pause and fix mistakes mutations cause to be underexpressed allowing damaged cell to divide

Question 4

How is DNA microarray used to answer questions

Answer 4

Levels of gene expression detected and Can detect what tumor suppressor genes are silenced as well as epigenetic tags (biomarkers)

Question 5

How can identical twins with same genome vary

Answer 5

Because of epigenome on rope of genome which is influence by environmental factors and can influence which are silenced or expressed