Chapter 7: Cardiac and Vascular Risk Flashcards
The term that describes the characteristics found in healthy people that are independently related to the subsequent development of coronary heart disease.
Cardiac risk factor
__________ cardiac risk factors include hypertension, hyperlipidemia, low HDL level, diabetes, tobacco use, and obesity.
Modifiable
__________ cardiac risk factors include age, gender, and family history of premature coronary heart disease in a first degree relative.
Nonmodifiable
Patients with a coronary heart disease risk equivalent have the __________ of coronary heart disease risk but have no yet experienced a coronary heart disease event.
Same level
What are the 3 coronary heart disease risk equivalent groups?
- Patients with 2 or more cardiac risk factors
- Patients with PVD, AAA, and symptomatic carotid artery disease
- Patients with type 2 diabetes
Study that has provided the richest source of data on predictors of heart and valvular disease. Current emphasis is on biomarkers and genetics as risk factors for heart disease.
The Framingham Heart Study
In the general population greater than 60 years, initiate pharmacologic treatment to lower SBP > ______ or diastolic BP > _______.
150; 90
In the general population less than 60 years, initiate pharmacologic treatment to lower diastolic BP > _____ and treat to goal of diastolic BP < _______
90; 90
In the general population less than 60 years, initiate pharmacologic treatment to lower SBP > _____ and treat to a goal of SBP < _____
140; 140
In the population greater than 18 with chronic kidney disease or diabetes, initiate pharmacologic treatment to lower SBP > ____ or diastolic BP > _____ and treat with goal SBP < ______ and diastolic BP < _______
140; 90; 140; 90
In the general population, including those with diabetes, initial hypertensive treatment should include one medication from what 4 classes of medications?
- Thiazide diuretic
- Calcium channel blocker
- ACE
- ARB
In the general black population, including those with diabetes, initial hypertensive treatment should include one medication from what 2 classes of medications?
- Thiazide diuretic
2. Calcium channel blocker
In the population greater than 18 years with chronic kidney disease, initial or add on antihypertensive treatment should include a(n) ____ or _____ to improve kidney outcomes. This applies to all chronic kidney diseases with hypertension regardless or race or diabetes status.
ACE or ARB
Can you use an ACE and ARB in the same patient?
No
If the goal blood pressure is not reached within _____ month(s) of treatment, increase the dose of the initial drug or add a second drug (thiazide diuretic, calcium channel blocker, ACE, or ARB).
One
What type of cholesterol is targeted with cholesterol medications?
LDL
______ dose statin used for:
Clinical atherosclerotic disease and age 21-75; includes MI, angina syndrome, prior arterial revascularization, CVA, TIA, or PAD
High
______ dose statin used for:
Diabetes age 40-75 and if 10 year atherosclerotic cardiovascular disease risk > 7.5%
High
______ dose statin used for:
Diabetics age 40-75 and if 10 year atherosclerotic cardiovascular disease < 7.5%
Moderate
Does diabetes accelerate artheromatous process that results in increased risk for atherosclerotic disease?
Yes
Is left ventricular hypertrophy associated with increased incidences of cardiovascular disease?
Yes
What study has developed and updated mathematical health risk appraisal models that relate risk factors to the probability of developing coronary heart disease within the next 10 years?
The Framingham Heart Study
Ex: 24 points = 9% probability of an event within 10 years
What are 4 modifiable risk factors for stroke?
- HTN
- Diabetes, hyperinsulinemia,and insulin resistance
- Asymptomatic aortic stenosis
- Afib
Two thirds of people who experience a first stroke have BP higher than _______.
160/95
What does CHADS2 stand for in regards to stroke risk factors?
C - Congestive heart failure (1 point) H - Hypertension (1 point) A - Age > 75 (1 point) D - Diabetes (1 point) S - Stroke or TIA (2 points)
8% of men and 11% of women will have a stroke within ____ years after an MI.
6
Post-MI development of Afib is a common source of _________.
Cardiogenic emboli
What are 5 risk factors for PVD?
- Diabetes
- HTN
- Hyperlipidemia
- Increased age
- Smoking