Chapter 7 Flashcards
which statement best describes linkage?
it is a condition in which two or more genes do not show independent assortment
in a testcross involving two heterozygous genes, equal numbers of recombinant and non recombinant progeny are produced.
from this result, what can be concluded ?
the genes are not linked
a recombination frequency of 5% translates to what distance on a genetic map?
5 m.u
three-point test crosses are often used to map genes
the two least frequency classes from such crosses usually represent which types of progeny?
double-crossover progeny
when two genes are linked but quite far apart their estimated map distance, based on recombination frequencies, is often an underestimation of their true map distance.
what is the explanation fro this underestimation?
some double crossover events go undetected since they do not lead to recombinant progeny
a genetic cross with two genes produces 400 offspring, and 20 of them have recombinant phenotypes.
what is the recombination frequency for this cross?
5%
20/ 400= 0.05–> 5%
the recombination frequency between genes A and B is 23%b
what is the distance between A and B in map units?
23 m.u
what information about recombination frequencies enables scientist to create linkage maps?
the recombination frequency is proportional to the distance between two genes
which statement explains why the recombination frequency between two genes is always less than 50 %
genes with a recombination frequency near 50% are unlinked and have an equal likelihood of being inherited together or separately
- bbTT x true breed male & BBtt true breed female
- BbTt x BbTt
results:
dark-eyed, short-tailed (BBtt)= 22
dark-eyed, long-tailed (BbTt or BBTT)= 56
light-eyed, long tailed (bbTT)=23
light-eyed, short-tailed (bbtt)=4
what is the most likely explanation for why Diane sees light-eyed, short-tailed (bbtt) progeny in this cross?
recombination
which statement is the definition of a map unit (centimorgan)?
it is the percent chance of a crossover between two locations on a chromosome
F1 test cross progeny phenotype broad =621 fast, zigzag= 623 zigzag=211 fast, broad= 221 fast= 215 zigzag, broad= 207 fast, zigzag, broad= 8 wild type= 7
select the order of the three genes
fbz
zbf
test progeny phenotype curved= 277 anomalous, buckled= 283 wild type= 5 anomalous, buckled, curved=5 buckled, curved= 128 anomalous= 132 anomalous, curved= 86 buckled= 84
calculate map distance between a and c
5+5+86+94 recombinants/ 1000 total = 0.18= 18 m.u.