Chapter 6

Question 1

what is a proband?

Answer 1

an affected individual in a pedigree who brings the family to the attention of the medical community

Question 2

which of the statements about x-linked recessive traits is false ?

Answer 2

they can be passed from father to son

Question 3

a male with a rare autosomal dominant trait marries a phenotypically normal woman.

what proportion of their children should show the trait?

Answer 3

one-half

Question 4

if a man exhibits a y-linked trait, what proportion of his sons should also be affected?

Answer 4

all of them

Question 5

which of the statements cannot occur with x-linked dominant inheritance for a rare trait?

Answer 5

an affected man can pass on the trait to his son

Question 6

consider the list:
usually appears in both sexes with equal frequency
both parents can transmit the trait to their offspring
affected offspring most commonly have an affected parent
unaffected parents do not transmit the trait
does not skip generations

which of the inheritance patterns best fits the pedigree characteristics described in the list?

Answer 6

autosomal dominant