Chapter 4 Flashcards

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1
Q

in the XX-XO mechanism of sex determination, which of the following statements is true?

males have 1 chromosome (XO) at high temperatures and 2 X chromosomes at low temperatures (XX)
males have 2 X chromosomes (XX) and females have one X chromosome (XO)
females have 2 Z chromosomes and males have 1 Z chromosome (ZO)
males have 1 X chromosome and 1 Y chromosome (XY)
females have 2 X chromosomes (XX) and males have one X chromosome (XO)

A

females have 2 X chromosomes (XX) and males have one X chromosome (XO)

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2
Q

in humans, what normally results in the male sexual phenotype?

the presence of two Z chromosomes (ZZ)
the presence of only one X chromosome (XO)
the presence of the SRY gene on the Y chromosome
the presence of the Xist gene on the X chromosome
the presence of one X chromosome and one W chromosome (XW)

A

the presence of the SRY gene on the Y chromosome

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3
Q

humans with only one sex chromosome (XO) usually have underdeveloped sexual characteristics and are sterile
what is this condition called ?

nondisjunction 
androgen-insensitivity syndrome 
Lyon hypothesis 
klinefelter syndrome 
turner syndrome
A

Turner syndrome

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4
Q

a human male with the chromosome constitution of XXXYY would contain how many Barr bodies in his somatic cells?

1
4
2
0
3
A

2

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5
Q

normally in humans a mutant gene on the Y chromosome will be inherited in which way?

half of the sons of a parent with the mutant gene will receive it and half will not; none of the daughters will receive it
half of the sons and daughters of a parent with the mutant gene will receive it and half will not
one-quarter of both the sons and daughters of a parent with the mutant gene will receive it and the rest will not
all of the daughters of a parent with the mutant gene will receive it but none of the sons will
all of the sons of a parent with the mutant gene will receive it but none of the daughters will

A

all of the sons of a parent with the mutant gene will receive it but none of the daughters will

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6
Q

the white-eyed mutation in drosophila, studied by Thomas hunt Morgan, was the first clear case of sex-linked inheritance.
when Morgan crossed a white-eyed female with a red-eyed male, what phenotypes were present in the offspring?

one-half of both females and males had red eyes and one-half had white eyes
all of the females had white eyes and all of the males had red eyes
all of the males had white eyes and all of the females had red eyes
all of the offspring had red eyes
all of the offspring had white eyes

A

all of the males had white eyes and all of the females had red eyes

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7
Q

which term describes the situation, for x-linked genes, in human and drosophila males who only have one X chromosome?

dioecious
homozygous 
homogametic 
hemizygous 
heterozygous
A

hemizygous

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8
Q

x-linked red-green color blinds in humans is a recessive condition.
which statement is true?

a color-blind woman must have a color-blind mother
a color-blind woman must have a color-blind father
a color-blind man must have a color-blind father
a color-blind man must have a color-blind mother
a man with normal vision cannot have a had a color-blind father

A

a color-blind woman must have a color-blind father

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9
Q

In butterflies, sex is determined by the ZW sex‑determination system. Female butterflies are heterogametic and have both a Z sex chromosome and a W sex chromosome for sex determination. In contrast, male butterflies are homogametic and have two Z sex chromosomes.
Select all of the relatives from which a female butterfly could have inherited her Z sex chromosome.

paternal grandmother

father

maternal grandfather

mother

A

paternal grandmother

father

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10
Q

Which statements describe Y‑linked traits?

The trait is passed down to a son by his father.

All male offspring of affected fathers will express the trait.

Males have a higher probability of inheriting the trait from their mothers.

At least 50% of the male and female offspring will inherit the trait.

Male offspring of a female with the phenotype will also express the phenotype.

A

The trait is passed down to a son by his father.

All male offspring of affected fathers will express the trait.

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11
Q

classify whether each gene regularly exists in a hemizygous state.

a muscular dystrophy gene on the x chromosome in a normal human male

a muscular dystrophy gene on an X chromosome in a normal human female

a gene chromosome 21 in an individual with down syndrome

a transgenic gene inserted into only one chromosome of a mouse

A

a muscular dystrophy gene on the x chromosome in a normal human male
a transgenic gene inserted into only one chromosome of a mouse

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12
Q

classify which gene does not regularly exists in a hemizygous state.

a muscular dystrophy gene on the x chromosome in a normal human male

a muscular dystrophy gene on an X chromosome in a normal human female

a gene chromosome 21 in an individual with down syndrome

a transgenic gene inserted into only one chromosome of a mouse

A

a muscular dystrophy gene on an X chromosome in a normal human female

a gene chromosome 21 in an individual with down syndrome

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13
Q

Hemophilia is called “the royal disease” because many European royal families had members with the condition. Hemophilia is a recessive, X‑linked disorder. Queen Victoria was unaffected by hemophilia, but was a carrier of the hemophilia gene (XHXh). Suppose Queen Victoria’s husband, Prince Albert, was affected with hemophilia (XhY).

What is the percent probability that a son of Queen Victoria and Prince Albert would be unaffected by hemophilia?

What is the percent probability that a daughter or son of Queen Victoria and Prince Albert would be affected by hemophilia?

What is the percent probability Queen Victoria and Prince Albert would have one affected male and then one affected female?

A

probability of unaffected son: 50%

probability of affected child: 50%

probability of one affected male and then one affected female: 50%

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14
Q

A man, Joe, has classic hemophilia, an X‑linked recessive disease.

Classify each person depending on whether or not Joe could have inherited the hemophilia gene from him or her.

maternal grandmother
maternal grandfather
paternal grandmother
paternal grandfather

A

could have inherited:
maternal grandmother
maternal grandfather

could not have inherited:
paternal grandmother
paternal grandfather

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15
Q

A man with normal vision, XB Y, and a woman who is a carrier for color blindness, XB Xb, mate. How many total phenotypes result from this cross?

What percentage of female offspring will be color‑blind?

If the mother were color‑blind, what percentage of male offspring would be color‑blind?

A

number of phenotypes: 3
color‑blind female offspring: 0%
color‑blind male offspring: 100%

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16
Q

Identical, or monozygotic, twins develop from a single egg fertilized by a single sperm. Monozygotic twins are genetically identical because they originate from a single zygote that split into two.

Caroline Loat and her colleagues examined nine measures of social, behavioral, and cognitive ability in 1000 pairs of both male and female identical twins. Their study found that pairs of male twins tended to be more alike in their prosocial behavior, peer problems, and verbal ability scores than pairs of female twins.

Which statement explains this observation?

Interacting genes on the X and Y chromosomes in the brains of males results in identical twins with more similar behaviors.

Identical male twins express the same X‑linked alleles in their neural cells, because males undergo random X‑inactivation.

Females are mosaic for the expression of heterozygous X‑linked loci, because females undergo random X‑inactivation.

Male twins have similar expression levels of X‑linked genes, because the Y chromosome silences expression of X chromosome genes.

A

Females are mosaic for the expression of heterozygous X‑linked loci, because females undergo random X‑inactivation.

17
Q

Color blindness is a sex‑linked recessive trait. A female is color blind in one eye, but not both.
Select the explanation for this condition.

all X chromosomes are inactivated

female has XO genotype

silencing of different X chromosomes

Is it possible for a male to have different color‑blindness phenotypes in each eye?

yes, in an XXY male with a different active X in each eye

yes, in an XYY male where each eye has alternate Y inactivation

no, since trisomy of the sex chromosomes is lethal

no, since XXY males lack X‑chromosome inactivation

A

silencing of different X chromosomes

yes, in an XXY male with a different active X in each eye

18
Q

Select the definition of aneuploidy.

the addition or loss of less than a full set of chromosomes or chromosome pairs

a complete chromosome set or an exact multiple of the haploid chromosome set

a chromosomal complement with at least three complete sets of homologous chromosomes

the number of chromosome sets that make up a complete genome

A

the addition or loss of less than a full set of chromosomes or chromosome pairs