Chapter 6 Flashcards
Opioids are considered first line therapy for (3)
-Pain associated with procedures (bone marrow biopsy)
-pain due to trauma or cancer (burns)
-visceral pain (appendicitis)
Majority of opioids are used to relieve
acute and chronic pain
Examples of opioids primarily indicated for preoperative sedation to reduce patient apprehension
Fentanyl (sublimaze, duragesic)
Alfentanil (alfenta)
Sufentanil (sufenta)
Opioids re also used to treat what and suppress what
Suppress cough
Treat diarrhea
Use of opioids is NOT contraindicated in what patients
Hypertensive patients
Opioid analgesics are contraindicated in patients with
Bronchial asthma or heavy pulmonary secretion
Convulsive disorders
Biliary obstruction
Head injuries
Pregnancy
Opioids should NOT be given if
A nonopioid analgesic will work
What is opium
Dried juice from unripe seed capsules of the opium poppy
Opioids are classified by mechanism of action at the receptor sites and include
Agonists
Mixed opioids
Antagonists
Agonists are drugs that
Occupy receptors and activate them
Antagonists are drugs that
Occupy receptors but do not activate them
Antagonists block receptor activation by
Agonists
Opioids act on the
CNS
Opioids binds to receptors in both the ____ producing an altered perception of reaction to pain
CNS and spinal cord