Chapter 6 Flashcards
Respiratory Pathway (nares -> alveoli)
Nares -> Nasal Cavity -> Pharynx -> Larynx -> Trachea -> Bronchi -> Bronchioles -> Alveoli
Inhalation
Muscles:
1. Diaphragm (contracts/flattens)
2. External intercostal muscles (contract)
Labored breathing neck and back muscles may also become involved
Intrapleural pressure lower than atomospheric pressure because expansion of chest cavity causes expansion of intrapleural space, decreasing its pressure
Exhalation
Passive:
Muscles recoil:
1. Diaphragm (relax)
2. External intercostal muscles (relax)
Active:
1. Diaphragm
2. External intercostal muscles
3. Internal intercostal muscles (contract)
4. Abdominal muscles (contract)
Surfactant
Reduces surface tension at air-liquid interface in alveoli
Prevents alveloi collapse
Vital Capacity (VC)
Sum of inspiratory reserve volume, expiratory reserve volume, and tidal volume
VC = IRV + ERV + TV
Respiratory Homeostasis
If CO2 levels too low, brain decreases respiratory rate to raise CO2 levels
Immune Mechanisms in Respiratory System
- Vibrissae in nares
- Lysozyme in mucous membranes (Enzyme in nasal cavity, saliva, and tears that degrades peptidoglycan preventing infection)
- Mucociliary escalator
- Macrophages in lungs
- Mucosal IgA antibodies
- Mast cells
Bicarbonate Buffer System
Respiratory Failure
- Ventilation slows
- Less CO2 blown off
- Buffer equations shifts to right and more H+ generated
- Results in lower pH of blood
Lung Gas Exchange
Relies on passive diffusion of oxygen and carbon dioxide
Facilitated by:
* Thin alveolar walls
* Multiple subdivisions of respiratory tree
* Differences in partial pressure of O2 and CO2
Lung Gas Exchange
Relies on passive diffusion of oxygen and carbon dioxide
Facilitated by:
* Thin alveolar walls
* Multiple subdivisions of respiratory tree
* Differences in partial pressure of O2 and CO2
Total Lung Capacity
Vital capacity (maximum volume of air that can be forcibly inhaled/exhaled) + residual volume (air that always remains in lungs to prevent alveoli from collapsing)
Intrapleural Space
Bounded by parietal and visceral pleurae
* Contains small amount of fluid
* Introducing more fluid/air into intrapleural space can fill space causing collapse
Epiglottis
Covers glottis during swallowing
Ciliated Epithelial Cells
Line the trachea and bronchi