Chapter 5 - The Biological Basis of Behaviour Flashcards
Central Nervous System vs Peripheral Nervous System
CNS is composed of the brain and spinal cord while the peripheral nervous system is composed of appendages and body.
Components of Central Nervous System
Brain, Spinal Cord, Optic Nerve, Retina
Components of Peripheral Nervous System
Cranial Nerve, Spinal Nerve, Somatic Nervous System, Autonomic Nervous System
Components of nerve cells
Soma, dendrite, axon and axon terminal
Glial Cells
Cells that povide structural support to the brain, 4 different types of glial
Types of Brain Cells
Neurons and Glial Cells
Parts of the synapse
Synaptic Vesicles, Neurotransmitters, Synaptic cleft
Types of neurons
Unipolar, bipolar, Multipolar
Unipolar Neurons
Most simplistic form of a neuron with a singular protrusion, found most commonly in invertebrates
Bipolar Neurons
Neurons with two protrusions image the basic image of a neuron, most common as sensory neurons, who receive a single signal.
Multipolar Neurons
Most complicated and complexe set of neurons that branch off in an indeterminate number of branches, the most common neuron among all of them.
Action potential
Interruoted concentration gradient that falls down the axon of the neuron to send a signal. Potassium enters neuron through voltage gated channels.
Concentration gradient of a neuron
Negative inside neuron positive outside neuron.
Potassium inside neurons, Sodium outside of neurons
Resting potential
The resting voltage that neurons have outside of any action potential around -70 mV
Threshold Potential
The necessary voltage to reach to continue an action potential along the length of the axon the necessary voltage to open the voltage-gated channels. Approx -55 mV
What occurs in the Synapse
The neurotransmitters open up channels that allow the first influx of sodium into the neuron that has a butterfly effect and leads the electrical current down the axon.
Repolarization
Action potential causes potassium channels to open aswell so as the positive sodium enters potassium leaves and rebalances the the charges, at which point sodium-potassium exchange pumps restores the concentration imbalance, the slow closing of the potassium channels causes a refractory period where the neuron can no longer execute am action potential.
Absolute Refractory period
The period in which an action potential is actively taking place and thus another action potential is not possible.
Relative Refractory Period
A brief period of time after an action potential where a large stimulus is required to get the neuron to fire due to hyperpolarization
Strong vs Weak Stimulus
Speed of the Action Potential
Myelin Sheath
A covering of the axon that increases the speed of action potential by only needing depolarization at the nodes of Ranvier. Found normally in the Central Nervous system, White matter has a higher concentration of myelin.
Reflex Arc
The almost instantaneous reaction that uses interneurons inside the spinal cord to react to a stimulus.
Amino Acids
A category of small-molecule neurotransmitters, includes Glutamate and GABA.
Monoamines
A small-molecule neurotransmitter, sub-categories include catecholamines and Indolamines. Neurotransmitters that are synthesized from a single amino acid.
Catecholamines
A monoamines that includes Dopamine and Norepinephrine
Indolamines
A monoamine that includes serotonin.
Acetylcholine
A self categorized small-molecule neurotransmitters. Controls skeletal muscles, alzheimers associated with low levels of ACh
Unconventional Neurotransmitters
Breaks down to soluble gases and endocannabinoids
Endocannabinoids
Includes the neurotransmitters anandamide
Large-Molecule Neurotransmitters
Neuropeptides, breaks down to specifically endorphins.
Agonist
A chemical that mimics the action of a neurotransmitter when it binds with the neurotransmitters receptor site.
Antagonist
A chemical that blocks the action of a neurotransmitter when it binds with the neurotransmitters receptor site.
Dopamine
Contributes to control of voluntary movement, is very integral to the “reward pathway” degeneration of of DA neurons is responsible for Parkinson’s.
Reward Pathway
Stimulation of a portion of the brain that makes animals have a favourable reaction and want more stimulation.
Dopamine Agonists
Cocaine and amphetamines.
Serotonin (5-HT)
Involved in regulation of sleep and wakefulness, eating, aggression. Prozac and antidepressant affect serotonin re-uptake.
Norepinephrine
Brain arousal and other functions, mood hunger sleep enhanced by amphetamines and methamphetamines, both hormone and neurotransmitter AKA noradrenaline
GABA
Gamma-aminobutyric, main inhibitory transmitter, regulates anxiety and sleep/arousal, Valium and similar antianxiety drugs work at GABA synapses.
Glutamate
Main excitatory neurotransmitter in the nervous system, participates in learning and relay of sensory information
Anandamide
Binds to the same receptors as THC
Endorphins
Painkillers
Neural Plasticity in development
Growth of dendrites and axons, Synaptogenesis, Pruning, Myelination
Long-term potentiation
the ability for two neurons to firs simultaneously.
Neural Plasticity following injury
Brain Regions can sometimes take over functions previously performed by others
Stem Cell Research
To produce all types of cells from a stem cell basis
Neurogenesis
Creation of new neurons in the adult brain
Meninges
Dura Mater, Arachnoid Mater, Pia Mater
Cerebrospinal Fluid
Provides the brain with nutrients and protection against the outside.
Franz Joseph Gall
Believes that the mind and the body are not separate entities and that all mental functions arise from the brain.
Phrenology
Study of the brain based off the size and shape of skull.
Frontal Loba
Performs functions that coordinate other brain areas, motor planning , language, and memory
Primary motor Cortex
Part of the frontal lobe that’s responsible for bodily movement.
The cortical homunculus
The sensory neurons in a single area of the body.
Prefrontal Cortex
Responsible for thinking and language
Brocas Area
Language portion of the prefrontal cortex.
Phineas Gage
Guy who got a bar through his head
Parietal Lobe
Process touch information, integrates vision and touch
Temporal Lobe
Process if auditory information language and autobiographical memory
Wernickes Area
Part of the temporal lobe involved in understanding speech.
Occipital Lobe
Vision
Basal Ganglia
Involved in goal directed motor control, associated with reward pathway.
Limbic System
Loosely connected structure, does stuff for smell motivation memory and emotion.
Thalamus
Command center and relay center, except center.
Hypothalamus
Part of the brain that regulates the endocrine system.
Hippocampus
Part of the brain that deals with memory.
Clive Wearing
The guy that forgets really fast, problem with Hippocampus
Amygdala
Deals with emotions
Brain Stem
Contains Midbrain and Hindbrain
Midbrain
Part of the brain that deals with movement and visual stimuli
Hindbrain
Cerebellum, Pons, Medulla
Cerebellum
Deals with body movement and position and balance.
Medulla
Part of the brain stem involved in basic functions, such as heartbeat and breathing.
Reticular Activating System
Responsible for arousal and consciousness.
EEG
Records the brains electrical activity at the surface of the skull.
CT scan
using multiple X-rays to construct three dimensional images.
MRI
Technique using strong magnetic fields to indirectly visualize brain structure.
PET Scan
An invasive technique that measures glucose consumption levels
fMRI
Technique that uses magnetic fields to visualize brain activity using the BOLD Response.
Problems with fMRI
BOLD Response doesn’t directly mean brain activity.
Transcranial Magnetic Stimulation
A technique that applies strong and quickly changing magnetic fields to the surface of the skull that can either enhance or interrupt brain function.
Neuroanatomical techniques
Golgi stain, Nissl Stain, Electron Microscopy
Golgi Stain
revealing silhouettes of neurons with a very dark dye
Nissl Stain
A stain that reveals the soma of the neurons.
Electron Microscopy
A Microscopy technique used to study the fine details of cellular structure.