Chapter 5: Integumentary System Flashcards
functional characteristics of integumentary system
- protection
- regulation of body temperature
- excretion
- vitamin D synthesis
- sensory reception
protection
cushions organs and protects from bumps, chemicals, water loss-UV radiation
regulation of body temperature
- vasodilation/vasoconstriction of capillary network
- sweat glands
- adipose tissue of hypodermis
excretion
urea, salts, and water loss through sweat
Vitamin D Synthesis
(cholecalciferol) is produced photochemically in the skin from 7 dehydrocholestrol
sensory reception
sensory receptors (nerve endings) keeps us aware of conditions at the body’s surface.
the integumentary system is composed of:
- integument (skin): largest organ
- appendages: sweat and sebaceous (oil) glands, hair and nails
- Accounts for 7-15% of body weight
- varies in thickness from 1.5-4.4mm
- Divided into 2 distinct layers:
1. Epidermis
2. Dermis
3. Hypodermis/Superficial Fascia
Epidermis
thick superficial epithelial layer
Dermis
deep fibrous connective tissue later
Hypodermis/Superficial Fascia
fatty later that lies deep to the dermis
-not part of the integumentary system
Epidermis
- keratinized stratified squamous epithelium
- contains 4 main cell types
1. Keratinocytes
2. Melanocytes
3. Tactile epithelial cells (Merkel cells)
4. Dendritic Cells (Langerhans cells)
Keratinocytes
most abundant cell type in epidermis
LOCATION: stratum spinosum.
- produce keratin, a touch fibrous protein that protects epidermis
- produce antibodies and enzymes; detoxify harmful chemical exposure
-keratinocytes arise from deep epidermis and are pushed to skin’s surface, keratin replaces cytoplasm and cells at surface are dead
Melanocytes
LOCATION: stratum basale later; manufacture and secrete pigment-melanin-to be transferred to keratinocytes
Tactile epithelial cells (Merkel Cells)
LOCATION: stratum basale layer; attached to disc-like sensory nerve endings
Dendritic Cells (Langerhans Cells)
LOCATION: stratum spinosum; part of immune system macrophage; the cells endocytosis or foreign antibodies
Layers of the Epidermis
- stratum basale (stratum germinativum)
- stratum spinosum (spiny layer)
- stratum granulosum (granular layer)
- stratum lucidum (clear layer)
- stratum corneum (cornified or horny layer)
Stratum Basale (Stratum Germinativum)
- deepest epidermis layer
- attached to the dermis layer
- germinating layer where rapid mitosis of keratinocytes is occuring
Stratum Spinosum (Spiny Layer)
- spine-like extensions of keratinocytes
- not seen in living cells only histology slides