Chapter 5: Integumentary System Flashcards
Define: androgen
Generic term for an agent (usually hormone like testosterone) that stimulates development of male characteristics.
Define: Ductule
Very small duct
Define: Homeostasis
State of equilibrium of internal environment despite changes in external environment.
Define: Synthesize
Forming a complex substance by the union of simpler compounds or elements.
What are the 3 layers of the skin?
- Epidermis (Outermost)
- Stratum Corneum (Mid)
- Basal Layer
What are 2 important glands in the dermis that produce secretion?
- The sweat gland (Sudoriferous)
- Sebaceous (Oil) glands.
What are the 3 element words meaning fat?
- Adip/o
- Lip/o
- Steat/o
What are the 3 element words meaning skin?
- Cutane/o
- Dermat/o
- Derm/o
What are the 2 key element words for sweat?
- Hidr/o
- Sudor/o
What does “ichthy/o” stand for?
Dry, scaly.
What does “kerat/o” stand for?
horny (hard) tissue, cornea.
What does “melano” mean?
Black, describing colour of something.
What does “myc/o” mean?
Fungus (or fungi)
What does “onych/o” and “ungu/o” mean?
Nail
What are the 2 words for hair?
- Pil/o
- Trich/o
What does “scler/o” mean?
Hardening ; sclera (white of eye)
What does “seb/o” mean?
Sebum, Sebaceous
What does “squam/o” mean?
Scale
What does “xen/o” mean?
Foreign, strange
What does “xer/o” mean?
Dry
What does “-cyte” mean?
Cell
What does “-derma” mean?
Skin
What does “epi-“ mean?
Above or upon.
Give the tumour characteristics of Grade 1 cells.
- Tumour cells well differentiated.
- Close resemblance to tissue origin.
- Retain some specialized function(s).
Give the characteristics of grade 2 tumour cells.
- Moderately or poorly differentiated.
- Less resemblance to tissue of origin.
- More variation in size and shape of tumour cells.
- Increased Mitosis.
Give characteristics of grade 3 tumour cells.
- Increased abnormality in appearance, very slight resemblance to tissue of origin.
- Marked variation in shape and size of tumour cells.
- Greatly increased mitoses.
Give characteristics of grade 4 tumour cells.
- Very poorly differentiated.
- Abnormal appearance to extent that recognition of tumour’s tissue origin is difficult.
- Extreme variation in size and shape of tumour cells.
What is the system used for staging tumours?
TNM System (Tumour, node, metastasis).
What are the 3 basic criteria of the TNM system?
T - Size and invasiveness of primary tumour.
N - Area lymph nodes involved
M - Invasiveness (Metastasis) of primary tumour.
For the T, what are the 3 stage 1 designations?
TX - Primary tumour can’t be evaluated.
T0 - No evidence of tumour.
Tis - Stage 1: Tumour is in defined location, shows no invasion into surrounding tissues.
What are the stage 2 designations for T?
T1, T2, T3, T4.
- Primary tumour size and extent of local invasion.
- T1 = minimal invasion
- T4 = large with extensive local invasion into surrounding organs and tissues.
For the N, what are the 3 designations?
NX
N0
N1, N2, N3, N4
What is the tissue involvement for NX and N0?
NX: Regional lymph nodes that can’t be evaluated.
N0: Regional lymph nodes that show no abnormalities.
What is the tissue involvement for N1, N2, N3, N4?
Stage 3
- Degree of lymph node involvement and spread to regional lymph nodes.
- N1 = minimal spreading, N4 is intensive spreading.
For M, what are the 3 stages involved?
MX
M0
M1
What are the descriptions for MX, M0, M1?
MX - Distant metastasis that can’t be evaluated.
M0 - No evidence of metastasis.
M1: Presence of metastasis.
What is abscess?
Collection of pus at site of an infection.
What is alopecia?
Partial or complete loss of hair resulting from normal aging, endocrine disorder, or skin disease. (AKA Baldness)
What is Bowen Disease?
Early form of skin cancer, easily curable and characterized by red patch on the skin.
What is cellulitis?
Widespread, acute infection of skin and subcutaneous tissue.
What is chloasma?
Skin discolouration occurring in yellowish brown patches or spots.
What is comedo?
Small skin lesion of acne caused by accumulation of keratin, bacteria, and dried sebum.
What is decubitus ulcer?
Inflammation, sore, or skin deterioration caused by prolonged pressure from lying in 1 position that prevents blood flow to the tissues.
What is ecchymosis?
Discolouration consisting of a large, irregularly formed hemorrhagic area with colours changing from bluish black to greenish brown or yellow.