Chapter 5/8: Virus Attachment Entry and Uncoating Flashcards
What two components are involved in the interaction between a virus and its host?
Viral attachment proteins, Host cell receptor molecules
What are 4 locations of viral attachment proteins?
Tail fibers (Bacteriophage), Attachment spike in viral envelope (Influenza), Attachment spike on viral capsid (Adenovirus), Attachment protein on viral capsid (Poliovirus)
How intense of a variant must receptor proteins be for the virus not to be able to recognize the host?
Slight variant
What is arguably the most important part in the viral replication cycle?
Entry
What do the mechanisms for virus entry depend on?
Host cell
What is a major difference in virus entry in animals versus plants, fungus, bacteria, etc?
Cell walls
What are the three mechanisms for entry for a virus?
Endocytosis, Membrane fussion, Endocytosis plus membrane fusion
What are the only type of viruses capable of membrane fusion?
Enveloped viruses
What structure forms after endocytosis is initiated in a non-enveloped virus?
Endosome
What 2 possible things could help open up the host plasma membrane for the virus to enter the cytoplasm in endocytosis with/without membrane fusion?
Lipases, Low pH
What is typically required for viral entry into plant tissues?
Damage
What type of proteins aid in penetration of the bacterial cell wall?
Endolysin proteins
What component of a bacteriophage contains endolysin proteins?
Tail fibers
What serves as the viral peplomer to produce an endosome in influenza?
Hemagglutinin
What initiates incorporation of plasma membrane and viral envelope in influenza and HIV?
Fusion peptide
