Chapter 5 Flashcards
skin (cutaneous membrane) is important for what?
homeostasis
superficial layer that consists of keratinized stratified squamous epithelium resting on a basement membrane dead cells and avascular (no blood vessels so no constant supply of oxygen); die a lot b/c avascular
Epidermis
contains : keratinocytes (cells that make keratonin)
deep to epidermis and basement membrane; consists of loose connective tissue and dense irregular connective tissue
dermis
what are some examples of acessory glands in the skin?
- sweat glands
- sabaceous glands
- hair
- nails
skin contains ____ and ______ that are responsible for goosebumps
sensory receptors and arrector pili muscles
because the epidermis is avascular, how does it get oxygen and nutrients?
Must rely on diffusion of oxygen and nutrients from blood vessels in deeper dermis
what are the superficial cells made up of? why?
About 50% of cells in epidermis are too far from adequate blood supply to sustain life; superficial layers are made up entirely of dead cells
also known as superficial fascia or subcutaneous fat, is deep to dermis
Hypodermis
what does the hypodermis do?
- abundant blood supply
- anchors skin to muscle and bones
What’re the 5 functions of the integumentary system?
- protect
- sensation
- thermoregulation
- Excretion (of nitrogen containing wastes)
- vitamin D synthesis
process that enables nervous system to perceive changes in the body’s internal or external surroundings; critical to homeostasis: we need to recognize when we get in dangerous temperatures; sufficient ability to feel pain
sensation
process where waste products and toxins are eliminated from body; this helps maintains an electrolyte balance (don’t want too much or too little)
excretion
Why do we need Vitamin D?
Vitamin D is required for calcium ion absorption from small intestine; calcium ion is critical for nerve function, muscle contraction, building and maintaining bone tissue, and many other physiological functions
what two things make the epidermis stronger?
- desmosomes- link the epidermis together
2. manufacture of keratonin (which is a tough fiborous protein)- makes the epidermis less subject to mechanical stress
Describe the stratum basale layer.
- closest cells to blood supply in dermis; therefore most metabolically and mitotically active cells in epidermis
- in vitamin D synthesis and replacement of dead keratinocytes
- cells in this layer are alive and dividing
describe the stratum spinosm
- thickest layer
- sits on top of stratum basale so still close to blood supply
- also metabolically and mitotically active cells= alive
describe the stratum granulosum
- filled with keratin bundles or a lipid-based substance;
- both secreted by exocytosis
- cells slowly begin to die in this layer
describe the stratum lucidum
- narrow layer of clear, dead keratinocytes;
- found only in thick skin extra protective layer
describe the stratum corneum
– outermost layer of epidermis; consists of several layers of dead flattened keratinocytes with thickened plasma membranes; filled mostly with keratin bundles and little else
As keratinocytes in deeper strata divide, how do they get cells into superficial layers?
push cells above them into more superficial layers
How and where are keratinocytes replaced?
how: replaced by mitosis of cells
where: stratum basale and spinosum where blood supply is available for such activities
location and functions of epidermis subjects it to both physical and environmental stress; stratum corneum is continuously shedding dead cells that must be replaced to maintain integrity of epidermis; starts in basale then sheds in the corneum
keratonin life cycle
located in stratum spinosum; phagocytes of immune system; protect skin and deeper tissues from pathogens defense against invaders of deeper regions
lagerhans cells
in stratum basale; sensory (touch) receptors associated with small neurons in dermis:
mercel cells
stratum basale; produce melanin; protein skin pigment ranging from orange-red to brown-black
melanocytes
what’s the diff between thick and thin skin?
Thick skin: has all five epidermal layers and a very thick stratum corneum; does not have hair follicles but contains many sweat glands
thin: stratum lucidum is missing; only 4 layers