Chapter 5 Flashcards

1
Q

What is the largest organ system in the body?

A

Integumentary system

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2
Q

List the layers of epidermis starting deep to most superficial.

A

Stratum basale, stratum spinosum, stratum granulosum, stratum lucidum (thick skin), stratum corneum

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3
Q

What is the difference between thick and thin skin?

A

Thick skin possesses 5 layers - stratum lucidum while thin skin only has 4 layers

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4
Q

What does melanin do and what cell produces melanin?

A

Melanin serves as a protection against UV radiation and gives skin and hair its pigmentation. The melanocytes produces melanin.

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5
Q

Why do the cells in the stratum granulosum look grainy?

A

Has keratin and keratohyalin that accumulates into lamellar granules.

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6
Q

What is the name of the protein that is found in the stratum lucidum?

A

Eleidin

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7
Q

How often is our stratum corneum getting replaced?

A

Every 4 weeks

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8
Q

What are the two layers of the dermis?

A

papillary and reticular layers

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9
Q

What are the two forms of melanin and what color do they produce?

A

Eumelanin - black and brown
Theomelanin - red

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10
Q

How long does it take for melanin synthesis to peak after UV exposure?

A

10 days post-exposure

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11
Q

Define hair follicle, hair shaft, and hair root.

A

Hair follicle - epidermal penetration of the dermis
Hair shaft - hair not anchored to follicle (usually at skin’s surface)
Hair root - anchored in hair follicle below the surface of the skin

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11
Q

What part of the nail is rapidly dividing?

A

Nail root

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11
Q

Name and define the three phases of hair growth.

A

Anagen phase - cell divides rapidly at hair root and push hair up and out
Catagen phase - transition from hair follicle’s active growth
Telagen phase - hair is at rest with no new growth

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11
Q

What are the two types of sweat glands and where do they empty their secretions?

A

Eccrine - duct has pore at skin’s surface that dumps sweat on skin
Apocrine - ducts empty in hair follicles

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11
Q

List the main functions of the integumentary system.

A

Protection, prevent dehydration, sensory organ, regulate body temperature and electrolyte balance, and synthesize vitamin D

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12
Q

What is the name of the antibacterial substance produced in sweat?

A

Dermcidin

13
Q

Name the types of touch that each cell responds to:

A

a. Meissner corpuscle – light touch
b. Pacinian corpuscle – vibration
c. Merkel cells – touch receptors found in stratum basale

14
Q

List the conversion of cholecalciferol to its active form and which organs are responsible for the conversions.

A

Epidermis synthesize vitamin D upon UV exposure which is vitamin D3 (cholecalciferol) -> liver converts to calcidiol -> kidneys convert to calcitriol (active form of vitamin D)

15
Q

What cell is affected by basal cell carcinoma and is this skin cancer benign or malignant?

A

Mitotically active stem cells in stratum basale – usually benign

16
Q

What is the most malignant skin cancer and which cells are affected?

A

Melanoma and affects melanocytes

17
Q

Define ABCDEEFG of skin cancer detection.

A

A – asymmetry
B – borders irregular
C - color – varied shades of brown and black
D – diameter – greater than 6 mm
E – evolving (changing shape)
E – elevated
F – firm
G – growing

18
Q

Acne is formed from the blockage of what that leads to inflammation and infection?

A

Blockage of hair follicles

19
Q

Define 1st degree, 2nd degree, 3rd degree, and 4th degree burns and which is most painful?

A

1st degree – superficial and only affects dermis
2nd degree – affects epidermis and part of dermis – most painful
3rd degree – affects all epidermis and dermis
4th degree – affects all skin layers + muscle and/or bone

20
Q

What causes keloid scarring?

A

Overproduction of scar tissue due to collagen formation that does not stop once wound is healed

21
Q

What is a common skin ailment that occurs during puberty and pregnancy?

A

Stretch marks