Chapter 45 Flashcards
Mode of transmission
Direct
•Direct: Physical contact between source of infection and new host
Mode of transmission
Indirect
Pathogens survive outside humans before causing infection
Antigen
Foreign substance – triggers immune response
Antibody
Protein made by the body in response to antigen
Active
Body makes antibodies without presence of clinical disease (example: tetanus vaccine
Passive
Antibodies made by another human or animal and given to another person – does not confer long-term immunity (example: tetanus immunoglobulin)
Killed virus vaccine example
inactivated polio/IPV)
Toxoid example
•Tetanus is a bacterial exotoxin
Live virus vaccine
MMR, varicella, what else?)
Recombinant form
(hepatitis B, pertussis) – DNA alteration of the organism
•Conjugated (Hib) – antigen/carrier protein
antigen/carrier protein
Reasons why parents don’t vaccinate
•Concern that vaccine is dangerous (autism, SIDS)
•Vaccine might not fully prevent disease
•Does not want government to monitor vaccination status
•The disease is not a threat anymore
•Side effects from vaccine do not justify benefit
•Belief that they can control child’s susceptibility to disease
•Poor experience prior – d/t:
–Procedure – site update
–Poor education on side effects and believe of reaction
Chicken pox varicella
- Agent: Herpes Varicella
- Transmission: Airborne, direct contact
- Systemic manifestations: Fever, malaise, headache, abdominal pain
- Skin manifestations: Clear, fluid-filled vesicles all over the body
- Treatment: Supportive
- Nursing: Isolation, symptom management
Cox hand foot and mouth disease
•Agent: Coxsackievirus A16, Enterovirus 71
•Transmission: Fecal-oral and respiratory routes
•Systemic manifestations: Fever, sore throat
•Skin manifestations
–Herpangina: Papulovesicular lesions in pharynx only
–Hand, foot, and mouth disease: Papulovesicular lesions on inside of cheek, gums, tongue, as well as hands and feet
•Treatment: Supportive
•Nursing: Isolation, topical lotions, cool drinks
Diphtheria
- Agent: Corynebacterium diphtheriae
- Transmission: Contact with nasal or eye discharge
- Systemic manifestations: Fever, anorexia, rhinorrhea, cough, stridor
- Oral manifestations: Tonsils, pharynx covered in thick, bluish-white patch
- Treatment: Antibiotics, IV antitoxin
- Nursing: Isolation, monitor for respiratory distress, administer antibiotics