Chapter 4.1 - Communicable Diseases Flashcards
What is a Pathogen?
an organism that causes disease
What is a bacteria?
A prokaryote that damages cells directly via toxins - e.g. salmonella, tuberculosis
What is a virus?
A non-living parasite that takes over host cells and uses their metabolic function to replicate until the host cell bursts and dies - e.g. HIV, influenza, TMZ
What is a Fungi?
a eukaryotic organism that uses hypae to form mycellum - uses spores to transmit - e.g. ringworm.
What is a protocista?
Unicellular parasites that feed off host cells to grow - e.g. malaria or blight.
What are some examples of primary human defence?
- skin
- blood clotting
- skin repair
- coughing / sneezing
- earwax
- lysosomes in tears
- cilia in trachea
What are some examples of secondary human defence?
- opsonins - cells that ‘mark’ antigens
- Phagocytes in immune system
What are some examples of passive plant defence?
- Cellulose cell wall
- lignin
- bark
- waxy cuticle
- stomatal closure
What are some examples of active plant defence?
- cell necrosis - controlled cell death to stop viruses spreading
- canker (death of cambium)
- oxidative bursts
- chemicals - Terpenoids + Phenols - antibac. + antifungal
- Bitter alkaloids - stop plants being eaten - callose deposited in plasmodesmata
What are opsonins?
Cells that bind to antigens and ‘mark’ them
also allows for easy binding site for phagocytes
What are agglutinins?
cells that bind to multiples antigens at once and bind all the pathogens together
What are anti-toxins?
cells that bind to toxins released by pathogens and neutralize them
What is the difference between the primary immune response and the secondary immune response?
The primary immune response is much slower than the secondary immune response, as the t memory cells are present during the secondary immune response and not the primary.
What is phagocytosis?
The process by which pathogens are engulfed and neutralised by phagocytes - lysosome enzymes within phagocytes destroy pathogen.
What are T helper cells?
Cells that bind to antigens + activate to mark them. They can also reproduce rapidly and differentiate into any T cell.