Chapter 4: Physiology Of Cells Flashcards

1
Q

What is passive transportation?

A

The process that moves substances through a membrane that does not require energy.

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2
Q

What is diffusion?

A

The tendency of small particles to spread out and distribute themselves evenly within a given space; from high concentration to lower.

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3
Q

What is a concentration gradient?

A

A measurable difference of solute concentration form one area of a solution to another

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4
Q

What is dynamic equilibrium?

A

The condition in which both sides of a membrane have equal concentrations of a solute.

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5
Q

What is simple diffusion?

A

When molecules or solutes pass directly through a membrane.

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6
Q

What is osmosis?

A

The diffusion of water through a selective permeable membrane to achieve dynamic equilibrium.

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7
Q

Define the 3 osmotic pressures as they relate to red blood cells.

A

Isotonic is when the pressure of a solution and that inside the cell are equal.
Hypotonic is the internal pressure of the cell is HIGHER than that of its environment. The cell will expand.
Hypertonic is when the internal pressure of the cell is LOWER than that of its environment. The cell will collapse.

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8
Q

What is facilitated diffusion?

A

A passive process that occurs when a specific membrane channel and transport protein carry the particles inside the cell.

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9
Q

What are the 2 types of facilitated transport and how do they work?

A

Channel-mediated transport: process by which water molecules, specific ions air other small water-soluble molecules can cross the membrane.
Carrier-mediated transport:
When molecules move in or out of the cell by their concentration gradient by passing through a membrane carrier.

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10
Q

Is filtration passive or active?

A

Passive.

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11
Q

What is active transport?

A

A process that uses energy to push or pull substances across the membrane against its concentration gradient.

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12
Q

What are the 2 types of active transport?

A

Transportation by pump

Transportation by vesicle

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13
Q

What are the 4 passive transport processes?

A

Diffusion
Simple diffusion
Osmosis
Facilitated diffusion

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14
Q

How does a sodium-potassium pump work?

A

3 sodium ions attach to sodium binding site of the pump on the intracellular side of the membrane. Simultaneously, an ATP binds to the pump. When the ATP breaks apart, energy is released and the pump changes shape, pushing the sodium ions out of the cell and attracting 2 potassium ions to their binding site. When the pump returns to its original shape, the potassium is drawn into the cell.

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15
Q

What are the 2 different types of “transportation by vesicle”?

A

Endocytosis

Exocytosis

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16
Q

What are the 4 types of endocytosis?

A

Receptor-mediated
Phagocytosis
Pinocytosis

17
Q

What is endocytosis?

A

When the membrane “traps” extracellular material and brings it inside the cell

18
Q

Describe receptor-mediated endocytosis.

A

Special receptor on the plasma membrane bind to specific molecules in the extracellular fluids and brings it inside

19
Q

What is phagocytosis?

A

“Cell eating”; type of endocytosis that engulfs large particles or microorganisms, forming vesicles around them for the expressed purpose of destroying it.

20
Q

What is pinocytosis?

A

“Cell drinking”; the endocytosis of liquids and the substance dissolved in it.

21
Q

What is exocytosis?

A

The process by which large molecules, packaged in vesicles, can leave the cells though they are too big to cross the membrane by other means. Waste and secretions exit the cell in this fashion.

22
Q

What is cellular metabolism?

A

The sum of all chemical reactions of a cell.

23
Q

What is a metabolic pathway?

A

The various types of chemical reactions

24
Q

What is catabolism?

A

The breakdown of molecules; usually resulting in energy

25
Q

What is anabolism?

A

The building of larger molecules from smaller ones; requires energy.

26
Q

What is an enzyme?

A

Functional proteins that serve as catalysts to nearly all chemical reactions.

27
Q

What is a catalyst?

A

They lower the amount of required energy needed to start a chemical reaction.

28
Q

What are the 3 main features of enzyme structure?

A
  • Enzymes are tertiary (3-faces) or quaternary (4-faces) with complex shapes.
  • Their molecules often have non-protein part called a co-factor. If the co-factor is an organic, it’s called a coenzyme.
  • Enzymes are “lock-and-key”; they a can only work on the molecules type they were created for.
29
Q

How are enzymes named?

A

Combing the root of the substance they act on and the suffix “-ase”

30
Q

What are the 2 key functions of an enzyme?

A
  • Every reaction that occurs in a metabolic pathway requires one or more enzymes.
  • Metabolic pathways can be regulated by activation and inactivation of certain enzymes
31
Q

What can destroy an enzyme’s ability to function?

A
  • An allosteric effector is a molecule or other agent changes the enzyme’s shape.
  • Denaturation is when environment factors, like pH or temperature, change the shape
32
Q

What is cell respiration and where does in the cell it take place?

A

The process by which break down nutrients (carbohydrates, fats, proteins) into carbon dioxide and water. It happens in the mitochondria.

33
Q

Define and explain glycolysis.

A

“Breaking of glucose”; the catabolic process of breaking down glucose into energy.

  • 1 glucose molecule is broken into 2 pyruvic acids.
  • If no oxygen is present, the pyruvic acid will continue on an anaerobic pathway(lactic acid)
  • If oxygen is present, the pyruvic acid continues on an aerobic pathway (citric acid and electron transport)
34
Q

Describe the citrus acid cycle (Krebs cycle)

A
  • Pyruvic acid (3-carbon) is broken into two 2-carbon molecules (acetyl), giving off one carbon dioxide and energy in the form of electrons that are carried off to the electron transfer system.
  • Each acetyl then binds to a 4-carbon (oxaloacetic acid) to form a 6-carbon (citric acid)
  • Enzymes then work on each citric acid, releasing two carbon dioxide molecules and energy (either ATP or electrons), creating the original 4-carbons at the beginning of the beginning of the chain.
  • The cycle repeats.
35
Q

Describe the electron transport cycle.

A
  • Electrons jump for 1 enzyme to the next, losing a small amount of energy as the go.
  • The “lost” energy is used to pump their accompanying proton (H+) out of the inner chamber to the outer chamber of the mitochondria.
  • The protons travel down their concentration gradient through ATP synthase and the energy is stored in the bonds of ATP.
  • The jumping electrons & their protons are captured by oxygen molecules to form metabolic water.
36
Q

Why is aerobic cellular respiration better for the cells than anaerobic?

A

In the anaerobic process, the pyruvic acid either converted back to glucose or stays as pyruvic acid. It releases no energy.

The aerobic process creates 36 to 38 ATP molecules from a single glucose molecule.