Chapter 4 Flashcards
when maternal nutrients fall below optimal who is receiving less nutrients- mom or baby
the baby,
when is the critical periode
first 2 months after conception
what is the critical periode
pre-programmed time periodes during embryonic and fetal development ehen specific cells organs and tissues are formed and intergrated
how many weeks is a pregnanacy
average of 38 weeks but usually given as 40 weeks because they mesure from the date of the first day of the last menstrual cycle ( 2 nonpregnant weeks)
how are physiological changes in pregnancies classifed
first half and last half
what are maternal anabolic changes
first half of pregnancy - build the capacity of the ,pthers body to deliver relatively large quantaties of blood, 0xygen and nutrients to the fetus baby growth 10%
what is maternal catabolic
2nd half of pregnancy- energy and nutrient stores and the heightened capacity to deliver stored energy and nutrient to the fetus predominates- baby growth : 90%
how does maternal body water change during preg
increaes 7 to 10 litters- due to amniotic fluid, plasma le, this is to increase blood flow and nutrients to the baby
why do women feel tiered during the first part of prego
surge in blood volume, this fades after 2-3 month
what ios the dilution effect
increase volume of water in the blood, blood levels of fat soluble vitamens increase. where there is a decrease in water soluble vitamins
what is the fetus prefered fuel
glucose
diabetogenic effect of pregnancy
maternal insulin resistance, for continued availabilty of glucose for the fetus- make the mom slightly carb intolerant in the third trimester
what happens in the first half of preg for carb conversions
estrogen and progesterone increses insulin production so that glucose is converted to glycogen and fat
what happens in the second half of preg to carbs
rising levels of hCS and prolactin inhibits the conversion of glucose to glycogen and fats. at the same time insulin resistance is building so that the baby will always have a supply
what is accelerated fating metabolism
the mom metabolism is converted to glucogenic amino acid utilization, fat oxidation,and ketone production
what is protein metabolism
the amino acids that go towards tissue building come from the food eaten during pregnancy
what happens in fat metabolism during pregnancy
accumulation of maternal fat store in the first half and enhance fat mobilization in second half- trigloyceride levels more than double then non-prego. the others also increase but not as much
why do maternal blood have more cholestrol
used by placenta to make hormones and to make for nerve and cell membrane formation
what are the function of the placenta
hormone and enzymme production, nutrient and gas exchange between the mother and fetus, removal of waste products from fetus
what factors determine what crosses the placenta
size and charge,lipid soluability, the []between mom and baby
what is easiest to cross the placenta
water and lipids-enzyme and insualin dontr cross at all
when and what is the critical periode
genetically progrmammed time periodes suring embryonic and fetal development when specific cells, organs, and tissues are formed and integrated - during first 2 months
what is the first organ that develops
the brain therefore if there is lacking nutrients it will take priority compared to muscles and liver
what is maturation
stabilization of cell number and size
what is IGF-1
primary growth stimulator of the baby promotes uptake of nutrients and inhibits tissue breakdown
what is SGA
Small for Gestational age- the wt is less than 10th percentile for gestational age the 2 pattern of growth are dSGA anf pSGA
dSGA
disproportionately small for gestational age: the wt is less than 10th percentile, but lenght and head circumferance are normal are skinny poorly developed muscles , look wasted and wrinkly due to malnutrtion in 3rd trimester
show good catch up growth
what is pSGA
wt, lenght and head circumferance are less than 10th percentile for gestational age- stay small for life and dont catch up
inutero longterm malnutrition
which babies have fewer health problems at birth but their catch up growth is slower
pSGA
what causes LGA
preprego obesity, poorly controlled diabetes, excessive weight gain,
how many cases of pregos leading to misscarridges
over30%
if there is a lack of vit d and e in the first trimester what might happen
a misscarridge
what can influence a preterm delivery
genital tract infections, insufficient flood flow, bleeding in uterus, preprego underweight, low weight gain in prego, stress, short interpregnanacy
epigenetics
role in silencing genes dose not change DNA
Thrifty phenotype
increase suseptibility to insulin resistance and weight gain in (bad nutrition)in utero