Chapter 33

Question 1

T/F: Grenz rays were a type of x-ray that were used to treat cancer.

Answer 1

False

Question 1

What is the SED50 for humans?

Answer 1

5 Gy

Question 2

T/F: The latent period occurs right after an acute exposure to radiation.

Answer 2

False

Question 3

This type of multi-hit chromosome aberration occurs when adjacent chromosomes suffer one hit each and recombine with each other:

Answer 3

Dicentric

Question 4

T/F: The LD50/30 is the amount of radiation to kill 30% of the population in 50 days.

Answer 4

False

Question 5

T/F: Isochromatids are the least common type of single-hit aberration.

Answer 5

True

Question 6

Which of the following is not a type of acute radiation sickness:

a. Hematologic syndrome
b. CNS syndrome
c. Hematopoietic syndrome
d. GI syndrome

Answer 6

c. Hematopoietic syndrome

Question 7

Another name for deterministic effects is:

Answer 7

nonstochastic

Question 8

This mean survival time for which type(s) of acute radiation syndrome is dose dependent:

1. Hematologic syndrome
2. Gastrointestinal syndrome
3. Central Nervous System syndrome

Answer 8

1 & 3

Question 9

Ovaries and testes respond differently to radiation exposure because of:

Answer 9

gametogenesis

Question 10

T/F: A dose of 5 Gy to the testes would result in temporary sterility.

Answer 10

False

Question 11

________ desquamation is considered the clinical tolerance for radiation therapy.

Answer 11

Moist

Question 12

T/F: Acute radiation lethality follows a non-linear, threshold curve.

Answer 12

True

Question 13

What is the correct order in which the following will occur after an acute exposure to radiation:

1. Manifest Illness
2. Prodromal period
3. Latent period

Answer 13

2
3
1

Question 14

T/F: Multi-hit chromosome aberrations are observed at rapidly increasing levels in exposures greater than 1 Gy.

Answer 14

True

Question 15

Erythrocytes are _________ sensitive to radiation because of their longer life span.

Answer 15

less

Question 16

What is the LD50/60 for humans:

Answer 16

3.5 Gy

Question 17

In which of the following multi-hit chromosome aberration is DNA actually re-arranged:

a. Ring
b. Dicentric
c. Reciprocal Translocation
d. Separation of Bases

Answer 17

c. Reciprocal Translocation

Question 18

T/F: Lymphocytes are the human cell type that is most commonly used for cytogenic analysis.

Answer 18

True

Question 19

Requires a dose of .01 Gy

Answer 19

Delay of Menstruation

Question 20

Requires a dose of 10 to 50 Gy

Answer 20

G.I. Syndrome

Question 21

Requires a dose of 2 to 10 Gy

Answer 21

Hematologic Syndrome

Question 22

Has a mean survival time that remains constant

Answer 22

G.I. Syndrome

Question 23

Requires a dose of 5 Gy

Answer 23

Permanent Sterility

Question 24

Requires a dose of > 50 Gy

Answer 24

CNS Syndrome

Question 25

T/F: The diagnostic beam always results in whole body exposure.

Answer 25

False

Question 26

The two most radiosensitive cells are:

Answer 26

lymphocytes and spermatogonia

Question 27

Multi-hit chromosome aberrations follow which dose response curve:

Answer 27

non-linear, non- threshold