Chapter 3: the chemistry of behavior Flashcards
define:
Ligand
substance that binds to a receptor
define:
Agonist
increases or mimics transmitter action
define
antagonist
decreases or interferes with transmitter action
list:
characterisitcs of ionotropic
2 points
- ligand- activated ion channels
- fast
list:
characteristics of metabotropic receptor
6 points
- signal proteins and G proteins
- slower
- longer-lasting
- more diffuse
- more varied
- two mechanisms
list:
criteria for neurotransmitter classification
5 points
- it is synthesized and stored in axon terminals of the presynaptic neuron
- it is released when action potentials reach axon terminals
- recognized by receptors on the post synaptic membrane
- it causes changes in a post synaptic membrane
- it causes changes in a postsynaptic cell
- blocking its release interferes with a presynaptic cell’s ability to affect a postsynaptic cell
list:
main neurotransmitter classes
- amino acid neurotransmitters
- monoamine neurotransmitters
- acetylcholine
list:
examples of amino acid neurotransmitters
- glutamate
- GABA
list:
types of monoamine neurotransmitters
2 points
- Catecholamines
- indolamine
list:
Examples of catecholamines
3 points
- norepinephrine
- epinephrine
- dopamine
list
example of indolamine
serotonin
list:
examples of neuropeptides
4 points
- oxytocin
- vasopressin
- opiod peptides
list:
examples of gases nitrous oxide
- nitric oxide
- carbon monoxide
list:
excitatory amino acids
2 points
- glutamate
- aspartate
list:
inhibatory amino acids
- GABA
- glycine
answer:
what is the most prevalent excitatory neurotransmitter
Glutamate
list:
ionotropic glutamate receptors
- NMDA
- AMPA
- KAR
Answer:
what is the metabotropic glutamate receptor
mGLuR
list:
characteristics of PCP (NMDA)
- Antagonist
- hallucinations
Answer:
what is termination of signal
reabsorption (reuptake) into surrounding glial cells
answer:
What is the most prevelant inhibitory neurotransmitter
GABA
gamma-amniobutyic acid
Answer:
where is GABA found
spinal motor neurons and CNS
Answer:
what does the ionotropic receptor open?
What happens?
- open Cl- channel
- cl- comes in
List:
Example of ionotropic receptors (GABA a)
3 points
- benzodiazapines
- alcohol
- GHB
Answer:
what does the metabotropic receptor open?
What happens?
- opens the K+ channel
- K+ goes out
List:
synthesis of Glutamate and GABA
- glutamine
- glutamate
- GABA
define
termination of signal
reabsorbtion into surrounding glial cells
Answer:
what are catecholamines synthesized from
tyrosine
Answer:
what is indolamine synthesized from
tryptophan
list
synthesis of catecholamine
- tyrosine
- DOPA
- dopamine
- norepinephrine
- Epinephrine
Answer:
why is the mesostriatal pathway important?
motor control