chapter 3: spleen

Question 1

5 functions of spleen

Answer 1

1. immunity
2. blood filtration
3. LT t lymphocyte storage
4. stores some WBC and platelets, large # of monocytes
5. hemopoietic organ in fetus

Question 2

spleen has a convex surface and a concave area which is the

Answer 2

hilum

Question 3

thick dense irregular fibroelastic CT found on some smooth ms cells and/or myofibroblasts to add strength

Answer 3

capsule

Question 4

dense irregular tissue

• thick, numerous, tortuous
• carry BV

Answer 4

trabeculae

Question 5

the lymphatic vessels of the spleen have no ____ (so as not to weaken the capsule when under pressure) but ____ do arise

Answer 5

afferents

efferents

Question 6

___ ____ further support splenic cells which are produced by reticular cells

Answer 6

reticular fibers

Question 7

general spleen function is

Answer 7

immunity

Question 8

__ __ area of spleen:

• next to capsule & septa
• B cell structures primarily (children, humoral immunity)
• PALs

Answer 8

white pulp

Question 9

PALs means

• LT storage for t cells
• t cell structure
• found around central artery

Answer 9

periarteriolar lymphoid sheaths

Question 10

most of the spleen is made of __ ___

• rapid blood filtration
• allows contact w/ blood borne foreign antigens

Answer 10

red pulp

Question 11

circulation in the red pulp is a combination of __ & ___ arteries

Answer 11

open

closed

Question 12

___ capillaries connect to fenestrated venous sinuses made of stave cells, which are unusually elongated endothelial cells (in red pulp), some blood is filtered

Answer 12

closed

Question 13

__ capillaries end abruptly and all blood enters red pulp to be filtered

Answer 13

open

Question 14

part of red pulp structure of:

• loose network of reticular fibers
• reticular cells
• MANY macrophages
• blood (wbc, rbc, platelets, monocytes)
• APCs (dendritic cells, macrophages)
• plasma cells

Answer 14

splenic cords