chapter 2: ECM Flashcards

1
Q

difference btwn epithelium and CT

A

CT consists mostly of intercellular components and limited # of cells

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2
Q

general fxn of CT

A

provide structural support
provide medium for exchange
defense/protection
storage of adipose

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3
Q

provide a structural support

A

reticular CT and bone

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4
Q

provide a medium for exchange

A

loose CT

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5
Q

defense/protection

A

loose areolar

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6
Q

storage of adipose

A

energy, thermoregulation, cushion organs

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7
Q

components of ECM

A

ground substance

fibers

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8
Q

important general trait of GAGs

A

hydrophilic

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9
Q

keratin sulfate
chondroitin sulfate
herapin sulfate
dermatin sulfate

A

sulfated GAGs

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10
Q

hyaluronic acid

A

nonsulfated GAG

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11
Q

smaller molecules

covalently bonded to PROTEINS

A

sulfated GAGs

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12
Q

large molecules
forms a dense molecule network
holds much WATER – important for DIFFUSION

A

non-sulfated GAGs

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13
Q

positive effects of inflammation

A

increase fluidity will aid cell movement

increase # of defensive cells

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14
Q

extra fluid and defensive cells come from:

A

leaky capillaries and venules

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15
Q

negative effects of inflammation

A

excessive swelling can damage BV, nerves and cells

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16
Q

excessive fluid remaining in interstitial spaces

A

edema

17
Q

protein core with many sulfated GAGs

A

proteoglycans

18
Q

laminin

fibronectin

A

adhesive glycoproteins

19
Q

MC CT protein

A

collagen

20
Q

______ collagen accounts for 90% of total body collagen and is known for great TENSILE strength

A

type I

21
Q

collagen type that does NOT stretch

A

type I

22
Q

with agin, fiber production _____ and fibers produced are _____

A

slows

weaker

23
Q

necessary for proper cross linking within the collagen I fiber

A

vit C

24
Q

composed of elastin and microfibrils that can stretch 150% of resting length

A

elastic

25
Q

commonly produced by fibroblasts and smooth muscle cells; important in BV and lungs

A

elastic

26
Q

as age increase, the # of elastic fibers will ____

A

decrease

27
Q

reticular is AKA

A

collagen type III

28
Q

fibers of ECM

A

collagen
elastic
reticular collagen (type III)

29
Q

collagen that is NOT affected with aging

A

reticular

30
Q

first fiber produced during wound healing; common in liver, bone marrow and lymph nodes

A

reticular