chapter 2: ECM Flashcards
difference btwn epithelium and CT
CT consists mostly of intercellular components and limited # of cells
general fxn of CT
provide structural support
provide medium for exchange
defense/protection
storage of adipose
provide a structural support
reticular CT and bone
provide a medium for exchange
loose CT
defense/protection
loose areolar
storage of adipose
energy, thermoregulation, cushion organs
components of ECM
ground substance
fibers
important general trait of GAGs
hydrophilic
keratin sulfate
chondroitin sulfate
herapin sulfate
dermatin sulfate
sulfated GAGs
hyaluronic acid
nonsulfated GAG
smaller molecules
covalently bonded to PROTEINS
sulfated GAGs
large molecules
forms a dense molecule network
holds much WATER – important for DIFFUSION
non-sulfated GAGs
positive effects of inflammation
increase fluidity will aid cell movement
increase # of defensive cells
extra fluid and defensive cells come from:
leaky capillaries and venules
negative effects of inflammation
excessive swelling can damage BV, nerves and cells
excessive fluid remaining in interstitial spaces
edema
protein core with many sulfated GAGs
proteoglycans
laminin
fibronectin
adhesive glycoproteins
MC CT protein
collagen
______ collagen accounts for 90% of total body collagen and is known for great TENSILE strength
type I
collagen type that does NOT stretch
type I
with agin, fiber production _____ and fibers produced are _____
slows
weaker
necessary for proper cross linking within the collagen I fiber
vit C
composed of elastin and microfibrils that can stretch 150% of resting length
elastic
commonly produced by fibroblasts and smooth muscle cells; important in BV and lungs
elastic
as age increase, the # of elastic fibers will ____
decrease
reticular is AKA
collagen type III
fibers of ECM
collagen
elastic
reticular collagen (type III)
collagen that is NOT affected with aging
reticular
first fiber produced during wound healing; common in liver, bone marrow and lymph nodes
reticular
