chapter 3: lymph nodes Flashcards

1
Q

two major functions of lymph nodes

A
  • filtration of lymph (via phagocytosis)

- humoral & cell mediated immunities

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2
Q

part of lymph node structure with dense irregular CT of moderate thickness containing trabeculae (septa)

A

capsule

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3
Q

____ lymphatics of the lymph node are incoming vessels while ____ lymphatics are outgoing. both contain valves

A

afferent

efferent

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4
Q

recessed area of lymph node where efferent lymph where blood will enter/exit

A

hilum

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5
Q

subcapsular sinus AKA

-first sinus to receive afferent (“dirty”) lymph

A

marginal sinus

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6
Q

in the lymph node, the ____ sinus passes through the cortex region, the ____ sinus passes thru the deep cortex/paracortex, and the ___ sinus passes through the medulla region

A

cortical
deep cortical
medullary

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7
Q

cells w/i all regions and sinuses of the lymph node are supported by a system of ___ ___ which are produced by reticular cells

A

reticular fibers

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8
Q

the ___ of a lymph node contains macrophages, reticular cells, follicular dendritic cells, dendritic cells, T cells, plasma cells

A

cortex

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9
Q

primary cortical cell type

A

B lymphocyte

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10
Q

phagocitic and humoral immunity is the activity that occurs in the ___ of the lymph node

A

cortex

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11
Q
  • type of lymph nodule that does not have a germinal center

- older nodules where naiive B cells congregate, as well as B memory cells

A

primary lymphoid nodule

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12
Q
  • lymph nodule that does have a germinal center and forms in response to a foreign antigen
  • active B cell division
A

secondary lymphoid nodule

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13
Q

two other names for the paracortex of the lymph node

-thins with HIV

A

thymus dependent zone

deep cortex

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14
Q

macrophages, reticular, some B, and dendritic cells are all found in the paracortex, but the primary cell type is a

A

T lymphocyte

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15
Q

-long term storage for T cells (can enlarge w/ Tcell stim)
-phagocytosis
-cell mediated immunity
is all activity that occurs in this area of the lymph node

A

paracortex

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16
Q

important structure of paracortex that is lined with cuboid cells and functions to promoste passage of B&T cells in from blood
-important blood/lymph crossover

A

high endothelial venules (HEVs)

17
Q

macrophages, reticular, some B & dendritic cells are found in the medulla, but the primary cell type is

A

plasma cell

18
Q

phagocytosis and some cell mediated immunity, but mostly humoral immunity due to antibody secretion occur in this area of the lymph node

A

medulla

19
Q

important medullar structures that are areas of lower cell density

A

medullary sinuses

20
Q

important medullar structures that are areas with HIGH cell density BT the sinuses

A

medullary cords