chapter 3: lymph nodes Flashcards
two major functions of lymph nodes
- filtration of lymph (via phagocytosis)
- humoral & cell mediated immunities
part of lymph node structure with dense irregular CT of moderate thickness containing trabeculae (septa)
capsule
____ lymphatics of the lymph node are incoming vessels while ____ lymphatics are outgoing. both contain valves
afferent
efferent
recessed area of lymph node where efferent lymph where blood will enter/exit
hilum
subcapsular sinus AKA
-first sinus to receive afferent (“dirty”) lymph
marginal sinus
in the lymph node, the ____ sinus passes through the cortex region, the ____ sinus passes thru the deep cortex/paracortex, and the ___ sinus passes through the medulla region
cortical
deep cortical
medullary
cells w/i all regions and sinuses of the lymph node are supported by a system of ___ ___ which are produced by reticular cells
reticular fibers
the ___ of a lymph node contains macrophages, reticular cells, follicular dendritic cells, dendritic cells, T cells, plasma cells
cortex
primary cortical cell type
B lymphocyte
phagocitic and humoral immunity is the activity that occurs in the ___ of the lymph node
cortex
- type of lymph nodule that does not have a germinal center
- older nodules where naiive B cells congregate, as well as B memory cells
primary lymphoid nodule
- lymph nodule that does have a germinal center and forms in response to a foreign antigen
- active B cell division
secondary lymphoid nodule
two other names for the paracortex of the lymph node
-thins with HIV
thymus dependent zone
deep cortex
macrophages, reticular, some B, and dendritic cells are all found in the paracortex, but the primary cell type is a
T lymphocyte
-long term storage for T cells (can enlarge w/ Tcell stim)
-phagocytosis
-cell mediated immunity
is all activity that occurs in this area of the lymph node
paracortex
important structure of paracortex that is lined with cuboid cells and functions to promoste passage of B&T cells in from blood
-important blood/lymph crossover
high endothelial venules (HEVs)
macrophages, reticular, some B & dendritic cells are found in the medulla, but the primary cell type is
plasma cell
phagocytosis and some cell mediated immunity, but mostly humoral immunity due to antibody secretion occur in this area of the lymph node
medulla
important medullar structures that are areas of lower cell density
medullary sinuses
important medullar structures that are areas with HIGH cell density BT the sinuses
medullary cords
