Chapter 3 pt 3 Flashcards
what re the EPS seen from antipsychotics and how are they treated
dystonia (spasm) of face, next and tongue
parkinsonism (resting tremor, rigidity, bradykinesia)
akathisia (feeling of restlessness)
tx: anticholinergics (benztropine, diphenhydramine), benzos and beta blockers for akathisia
what are the 6 main side effects seen from antipsychotics
EPS anticholinergic metabolic syndrome tardive dyskinesia neuroleptic malignant syndrome prolonged QTc
what are the more weight neutral 2nd generation antipsychotics with less of a risk for metabolic side effects
apriprazole or ziprazidone
tardive dyskinesia is more commonly seen with what antipsychoitcs
1st generation
patients on second generation antipsychotics need to be monitored for what and how
metabolic syndorme
blood pressure, BMI, weight, fasting blood glucose, lipid panel
high-potency antipsychotics (haloperidol and fluphenazine) have higher risk of what side effects
EPS
low-potency antipsychotics (chlorpromazine) have primarily risk of what side effects
anticholinergic and antiadrenerigic
what is seen in neuroleptic malignant syndrome
change in mental status autonomic instability (high fever, labile blood pressure, tachycardia, tachypnea, diaphoresis) lead pipe rigidity elevated CPK leukocytosis metabolic acidosis
cumulative risk of developing tardive dyskinesia from antipsychotics (especially 1st generation) is what
5% per year
thioridazine may cause what side effect
irreversible RETINAL PIGMENTATION at high doses
chlorpromazine may cause what side effect
deposits in LENS and CORNEA
what is the prognosis of schizophreniform disorder
1/3 recover completely
2/3 either have schizoaffective or schizophrenia
what is treatment of schizophreniform disorder
hospital (if necessary)
6 months antipsychotics
supportive psychotherapy
what DSM-5 criteria schizoaffective disorder
meets criteria for tether major depressive or manic episode during which psychotic symptoms consistent with schizophrenia are also met
delusion or hallucinations for 2 weeks in the absence of mood disorder (differentiates from mood disorder w/ psychotic features)
mood symptoms present for a majority of psychotic illness
patients with what personality disorder may have transient, stress related psychotic experiences
BORDERLINE
these are considered part of their underlying personality disorder and not diagnosed as a brief psychotic disorder