Chapter 3 pt 3 Flashcards

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1
Q

what re the EPS seen from antipsychotics and how are they treated

A

dystonia (spasm) of face, next and tongue
parkinsonism (resting tremor, rigidity, bradykinesia)
akathisia (feeling of restlessness)

tx: anticholinergics (benztropine, diphenhydramine), benzos and beta blockers for akathisia

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2
Q

what are the 6 main side effects seen from antipsychotics

A
EPS
anticholinergic
metabolic syndrome
tardive dyskinesia
neuroleptic malignant syndrome
prolonged QTc
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3
Q

what are the more weight neutral 2nd generation antipsychotics with less of a risk for metabolic side effects

A

apriprazole or ziprazidone

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4
Q

tardive dyskinesia is more commonly seen with what antipsychoitcs

A

1st generation

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5
Q

patients on second generation antipsychotics need to be monitored for what and how

A

metabolic syndorme

blood pressure, BMI, weight, fasting blood glucose, lipid panel

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6
Q

high-potency antipsychotics (haloperidol and fluphenazine) have higher risk of what side effects

A

EPS

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7
Q

low-potency antipsychotics (chlorpromazine) have primarily risk of what side effects

A

anticholinergic and antiadrenerigic

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8
Q

what is seen in neuroleptic malignant syndrome

A
change in mental status
autonomic instability (high fever, labile blood pressure, tachycardia, tachypnea, diaphoresis)
lead pipe rigidity
elevated CPK
leukocytosis
metabolic acidosis
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9
Q

cumulative risk of developing tardive dyskinesia from antipsychotics (especially 1st generation) is what

A

5% per year

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10
Q

thioridazine may cause what side effect

A

irreversible RETINAL PIGMENTATION at high doses

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11
Q

chlorpromazine may cause what side effect

A

deposits in LENS and CORNEA

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12
Q

what is the prognosis of schizophreniform disorder

A

1/3 recover completely

2/3 either have schizoaffective or schizophrenia

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13
Q

what is treatment of schizophreniform disorder

A

hospital (if necessary)
6 months antipsychotics
supportive psychotherapy

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14
Q

what DSM-5 criteria schizoaffective disorder

A

meets criteria for tether major depressive or manic episode during which psychotic symptoms consistent with schizophrenia are also met
delusion or hallucinations for 2 weeks in the absence of mood disorder (differentiates from mood disorder w/ psychotic features)
mood symptoms present for a majority of psychotic illness

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15
Q

patients with what personality disorder may have transient, stress related psychotic experiences

A

BORDERLINE

these are considered part of their underlying personality disorder and not diagnosed as a brief psychotic disorder

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16
Q

brief psychotic disorder is fairly rare, but can be seen in reaction to what

A

major stressor: bereavement or sexual assault

17
Q

what is the prognosis of brief psychotic disorder

A

high rates of relapse

almost all completely recover

18
Q

what is treatment of brief psychotic disorder

A

brief hospitalization (usually for workup, safety, and stabilization)
supportive therapy
course of antipsychotics
benzos for agitation

19
Q

what is the criteria for delusional disorder

A

one of more delusion for at least a month
does not meet criteria for schizophrenia
functioning in life not significantly impaired, and behavior not obviously bizarre

20
Q

what are erotomania type of delusions

A

delusions that another person is in love with the individual

21
Q

what are grandiose type delusions

A

delusions of having great talent

22
Q

what are somatic type delusions

A

physical delusions

23
Q

what are persecutory type delusions

A

delusions of being persecuted

24
Q

what are jealous type delusions

A

delusions of unfaithfulness

25
Q

what are mixed type delusions

A

more than one of the above

26
Q

what are unspecified type delusions

A

not a specified type as described above

27
Q

what is KORO

A

intesen anxiety of PENIS receding into the body, possibly leading to death

southeast asia (singapore)

28
Q

what is AMOK

A

sudden unproved outburst of violence, often followed by suicide

malaysia

29
Q

what is BRAIN FAG

A

headache, fatigue, eye pain, cognitive difficulties, and other somatic disturbance in male students

africa

30
Q

rank the prognosis in order from best to worst for these disorders: schizophrenia, mood disorder w/ psychotic features, schizophreniform, schizoaffective

A

mood disorder w/ psychotic features > schizoaffective disorder > schizophreniform disorder > schizophrenia

31
Q

what is schizotypal personality disorder

A

paranoid, odd or magical beliefs, eccentric, lack of friends, social anxiety,

32
Q

what is schizoid personality disorder

A

solitary activities, lack of enjoyment from social interactions, no psychosis