Chapter 1 Pt 2 Flashcards

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1
Q

what is seen in amphetamine/cocaine intox

A
euphoria
increased attention span
aggressiveness
psychomotor agitation
pupil dilation
hypertension
tachycardia
cardiac arryhtmias
psychosis (paranoia w/ amphetamine, formication w/ cocaine)
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2
Q

what is seen in amphetamine/cocaine withdrawal

A
post use "crash"
restlessness
headaches
hunger
severe depression
irritability
insomnia/hypersomnia 
strong psychological craving
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3
Q

what is seen in PCP intoxication

A
belligerence
impulsiveness
psychomotor agitation
VERTICAL/HORIZONTAL NYSTAGMUS
hyperthermia
tachycardia
ataxia
psychosis
HOMICIDALITY
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4
Q

what is seen in PCP withdrawal

A

may have recurrence of symptoms due to resorption in GI tract

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5
Q

what is seen in LSD intoxication

A

altered perceptual states (hallucinations, distortions of time and space)
election of mood
“bad trips” (panic reaction)
flashbacks (reexperience of sensations in absence of drug use)

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6
Q

what is seen in cannabis intoxication

A
euphoria
anxiety
paranoia
slowed time
social withdrawal
increased appetite
dry mouth
tachycardia
amotivational syndrome
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7
Q

what is seen in nicotine/caffeine intoxication

A

restlessness
insomnia
anxiety
anorexia

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8
Q

what is seen in nicotine/caffeine withdrawal

A
irritability
lethargy
headache
increased appetite
weight gain
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9
Q

what is Delirium Tremens (DTs)

A

delirium, agitation, FEVER, AUTONOMIC HYPERactivity, auditory and visual HALLUCINATIONS

typically within 2-4 days after cessation of EtOH but may occur later

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10
Q

how does one treat DTs

A

benzos and hydration

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11
Q

what is neuroleptic malignant syndrome (NMS)

A

fever, RIGIDITY, autonomic instability, clouding of consciousness, ELEVATED WBC/CPK
idiosyncratic, time-limited reaction

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12
Q

hoe is neuroleptic malignant syndrome treated

A

withhold neuroleptics
hydrate
consider DANTROLENE and/or BROMOCRIPTINE

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13
Q

what is serotonin syndrome

A
altered mental status
fever
agitation
TREMOR
MYOCLONUS
HYPERREFLEXIA
ataxia
incoordination
diaphoresis
SHIVERING
diarrhea

precipitated by use of two drugs with serotonin-enhancing properties

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14
Q

how does one treat serotonin syndrome

A

discontinue offentidn agenxts
BENZOS
CYPROHEPTADINE

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15
Q

what is a tyramine reaction/hypertensive crisis

A

hypertension, headache, NECK STIFFNESS, sweating, nausea, vomiting, visual problems
most serious consequences: STROKE and possibly DEATH

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16
Q

how does one treat a tyramine reaction/hypertensive crisis

A

nitroprusside or phentolamine

17
Q

what is acute dystonia

A

early, sudden onset of muscle spasm: eyes, tongue, jaw, neck

may lead to laryngospasm requiring intubation

18
Q

how does one treat acute dystonia

A

BENZTROPINE (cogentin) or DIPHENHYDRAMINE (benadryl)

19
Q

what is seen in lithium tox

A

nausea, vomiting, slurred speech, ataxia, incoordination, myoconus, hyperreflexia, seizures, nephrogenic diabetes insipidus, delirium, coma

may occur at any Li level (usually >1.5)

20
Q

how does one treat lithium toxicity

A

discontinue Li
hydrate aggressively
consider hemodialysis

21
Q

what is seen in TCA toxicity

A
primarily anticholinergic effects
cardiac conduction disturbances
hypotension
resp distress
agitation
hallucinations 
CNS stimulation
depression
seizures
22
Q

how does one manage TCA toxicity

A

monitor ECG
activated charcoal
cathartics
supportive treatment