Chapter 3/Cellular Structure, Proteins, and Metabolic Pathways Flashcards
Selective barrier: regulates passage in and out of cell and between organelles and cytosol
Membranes
-Detect chemical messengers
-Link cells together
-Anchor cell to extracellular matrix
Membranes
-Non polar fatty acids chains in the middle
-Polar regions oriented towards the surfaces of the membrane
Phospholipids bilayers
-Found in the plasma membrane
-Maintains fluidity
Cholesterol
-Amphipathic
-Associate with fatty acids in membrane
-Can span the entire membrane: transmembrane proteins
Integral membrane proteins
-Do not associate with fatty acids
-Located at the membrane surface bound to integral membrane
Peripheral membrane
-Transmembrane proteins
-Bind to specific proteins in the extracellular matrix
-Link to membrane proteins in adjacent cells
-Cells are joined physically
Integrins(membrane)
-Plasma membranes of cells are separated by about 20 nm
Desmosomes
‘Dense plaques’’ serve as anchoring points for cadherins
Desmosomes
-Cadherins extend into extracellular space and link up with cadherins of an adjacent cell
Desmosomes
-Leaves no space between adjacent cells
Tight Junction
-Occur in a band around the entire circumference of cell
Tight Junction
Form barrier that prevent movement of material through tissue
Tight Junction
-Protein channels that link the cytosols of adjacent cells
Gap junction
-Connexins from both cells join and form a protein-linked channel
Gap junction
-Small diameter (1.5 nm) limits what can pass
Gap Junction
Storage and transmission of genetic information
Nucleus
-Information coded in DNA molecules
-DNA also used to synthesize proteins
Nucleus
DNA is found in association with proteins called histones
DNA + Protein=Chromatin
-During cell division chromatin becomes condensed, forms chromosomes
Nucleus
Nuclear envelopes surrounds nucleus
-Two membranes
-Join together, form nuclear pores
-Associated with regions of DNA that contains for forms RNA found in ribosomes
Nucleolus
-Ribosomes are assembled then transferred to cytoplasm
Nucleolus
-Proteins factories
- Composed of protein and RNA
-Can be found attached to endoplasmic reticulum or floating free in the cytoplasm
Ribosomes
-Has ribosomes bound to its surface
-Packages proteins that are produced by ribosomes, sends them to Golgi apparatus
Rough ER
-No ribosomes
-Lipids are synthesized
-Detoxifies the cell
-Stores calcium
-Smooth ER