Chapter 3 - Biological Psychology Flashcards
How many nerve cells in the brain?
~100 billion
Define: dendrites
-Extensions that receive information from neighbouring neurons
What are spines on dendrites for?
Result of lack of spines?
- Increase surface area
- Down syndrome
Define: Soma
- Cell body
- Integrates information from dendrites then passes it along axon
Define: Axon
- Think “axe”; a thing that goes away from the body!
- Long extension leading away from soma
- Covered with myelin sheath
Define: Axon Hillock
- Think “hill”; the culmination of something
- Last site on soma where synaptic inputs are summed before going down axon
Define: Myelin sheath
- Fatty glial cells that insulates axons
- Improves speed and strength of signals
Define: Axon terminal (or terminal button)
- Knob at the end of the axon
- Transmits signals to dendrites, cell bodes, muscles
Define: Synapse
- Entire junction where axon terminal communicates with receiving neuron across synaptic cleft
- 100 trillion of them
Define: Synaptic cleft
-Actual space between neurons (axon and receptor site)
Define: Synaptic vesicles
- Spherical sacs containing neurotransmitters
- small NTs made onsite; lg. NTs made in soma
Define: Glial cells
- Support cells
- promote healing, clearing debris
Which disease is caused by demyelination?
Multiple sclerosis
Two kinds of myelinating glial cells?
- Schwann cells (PNS) [Think Schwinn tires psi)
- Oligodendrocytes (CNS) [Think oligarchy=Central]
Define: Blood Brain Barrier
- Glial cells (astrocytes) wrapped around brain blood vessels and capillaries
- Don’t let through large or water soluble molecules
What are neurons responding to, by generating electrical activity?
Neurotransmitters
Define: Resting potential
- When no NTs are acting on neuron but ready to fire
- polarized, selectively permeable membrane
- negative 60mV charge on inside of neuron
- +and- particles flowing back and forth membrane
Define: Threshold
- Stimulation from sensory receptor or another neuron causes a change in membrane permeability, and degree of polarity
- When electrical charge gets high enough compared to outside (~55mV)
- Causes action potential
Which kind of ions are inside and outside neuron in resting potential?
Outside: Na+ [Think “on” or outside the cell]
Inside: K+ and negative protein
Define: Action potential
-Electrical impulse that travels down axon and triggers release of NTs
Three rules to action potentials
- TAA [Think “ta-ta, buh-bye, no stopping me now”]
1. Threshold
2. All-or-none phenomenon
3. Absolute refractory
Regarding threshold, intensity of stimulation within a single neuron is communicated by…
the RATE of firing.
Regarding threshold, intensity in the nervous system overall is communicated by…
the RATE of firing and NUMBER of neurons firing.
Define and explain what it does: Absolute refractory
- Tim;e when another action potential is impossible
- Limits firing rate
- AP propagates only in one direction
Give 6 steps of action potential.
- Threshold of excitation; Na+ begins to enters cell; voltage spikes
- K+ begins to leave cell
- Na+ channels become refractory; no more Na+ enters cell.
- K+ continues to leave cell; voltage drops to resting level.
- K+ channels close; Na+ channels reset
- Voltage is below resting from extra K+; K+ diffuses away; voltage rises slightly to resting potential
Define: Nodes of Ranvier
- Gaps in myelination on axon where ion flow occurs to regenerate and speed up signal.
- “Saltatory conduction” [Think “sauter” or jumping]
Define: Presynaptic and postsynaptic neurons
- Presynaptic is sending neuron
- Postsynaptic is receiving neuron
3 steps of Neurotransmission
- Release NT
- Binding of NT
- Stopping NT activity
Factors determining excitatory or inhibitory action of NT depends on…
where and how much is released
Roles of 4 NTs
Dopamine: motor function and reward (too much=schizophrenia; too little=parkinsons)
Serotonin: mood and temperature regulation; aggression; sleep cycles
Acetylcholine: Muscle contraction (PNS); Cortical arousal (CNS)
Norepinephrine: Brain arousal; mood, hunger, sleep
3 ways NTs are inactivated
- 90% by re-uptake into presynaptic neuron
- Enzymes (MonoamineoxidASE; acetylcholinestrASE)
- Drift away
Division of nervous system
CNS>Brain (forebrain, brainstem)/Spinal cord
PNS>Autonomic (sympathetic, parasympathetic)/Somatic
Define: forebrain/cerebrum
- Several structures involved in sensory-info processing, memory, learning, emotion
- Includes cerebral cortex
- Includes corpus callosum
Define: corpus callosum
-Thick band of connecting and communicating fibres, connecting R and L hemisphere
Name the four lobes of the cortex
Lobes:
- Frontal
- Parietal
- Temporal
- Occipital