chapter 24 lipoglycopeptides Flashcards
1
Q
ADRs of lipoglycopeptides
A
- ototoxicity-can be transient or permanent
- nephrotoxicity
- “red man” syndrome if infused too quickly
2
Q
pharmacodynamics and pharmacokinetics of lipoglycopeptides
A
- vancomycin, telavancin (Vibativ), dalbavancin (Zeven)
- used for severe gram-positive infections-MRSA (resistant to 1st line abx)
- inhibits cell wall synthesis
- vancomycin-very narrow spectrum
- poor po absorption-given IV