Chapter 24 - Digestive System Flashcards
pharynx
Muscular driving of materials into the esophagus
esophagus
transport of materials to stomach
stomach
– Mechanical digestion with muscular contractions
– chemical digestion by acid and enzymes
small intestine
Enzymatic digestion and absorption of water, organic substrates, vitamins, and ions
large intestine
indigestible materials prepares for elimination
Integrated processes of digestive system
–Ingestion –Mechanical digestion and propulsion –Chemical digestion –Secretion –Absorption –Defecation
villi
fingerlike projections from surface of certain membranous structures
mucosa
glands and the gastric pits, mucous membrane layer of the stomach
submucosa
layer of areolar connective tissue under mucous membrane
Enteroendocrine cells
Secrete hormones that coordinate activities of digestive tract and accessory glands
regulation of digestive functions
– Local factors
– Neural mechanisms
– Hormonal mechanisms
visceral motor neurons
Control smooth muscle contraction
Short reflexes (local reflexes)
- Control small segments of digestive tract
* outside of CNS control - enteric nervous system
long reflexes
- in CNS
- Provide higher level control
- Stimulate large-scale peristalsis
- Parasympathetic motor fibers synapse in myenteric plexus
hormonal mechanisms
enteroendocrine cells:
– Enteroendocrine cells in digestive tract produce many peptide hormones
• Affect almost every aspect of digestion
– Travel through bloodstream to reach target organs
chyme
Partially digested food mixed w acidic secretions of stomach
rugae
wrinkles/gastric folds
gastric glands
– In fundus and body of stomach
– Each gastric pit communicates w/ several gastric glands
• Parietal cells
• Chief cells
– Secrete about 1500 mL of gastric juice each day
parietal cells
– Secrete intrinsic factor
• Glycoprotein - absorb vitamin B12
– secrete hydrochloric acid (HCl)
chief cells
– Secrete pepsinogen (an inactive proenzyme)
• Pepsinogen is converted to pepsin (an active proteolytic enzyme) by HCl
things absorbed in stomach
alcohol, ibuprofen
chemical digestion in stomach
digestion of carbohydrates (by salivary amylase) and lipids (by lingual lipase)
As stomach contents become more fluid,
• pH approaches 2.0
• digestion of proteins by pepsin increases
– Nutrients are not absorbed in stomach
exocrine cells
– Secrete alkaline pancreatic juice into small intestine
• About 1000 mL per day
• Contains digestive enzymes, water, and ions
pancreatic enzymes
– Pancreatic alpha-amylase - starch
– Pancreatic lipase -
– Nucleases - dna
– Proteolytic enzymes - proteins
liver secretes bile
(gall bladder)
• Into a network of narrow channels (bile canaliculi)
– Right and left hepatic ducts
– Liver has over 200 functions in three categories
- Metabolic regulation
- Hematological regulation
- Bile production
liver cells
- removes nutrients or toxins from blood
- removes and stores excess nutrients (C loading)