Chapter 23 - Respiratory System Flashcards

1
Q

respiratory system

A
  • exchange of gases

- moves air to and from exchange surfaces of lungs

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2
Q

mucus

A

along respiratory tracts

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3
Q

Respiratory defense system

A

nose removes large particles

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4
Q

Mucous cells and mucous glands

A

produces mucous to cover exposed surfaces

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5
Q

cilia

A

gather mucus, trapped debris, microorganisms toward pharynx to be swallowed

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6
Q

Alveolar macrophages

A

eat small particles that reach lungs

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7
Q

Bronchioles

A

– Bronchioles branch into terminal bronchioles
– Bronchioles have no cartilage
• Dominated by smooth muscle

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8
Q

autonomic nervous system

A

– Controls bronchioles diameter by regulating smooth muscle

– Controls airflow in lungs

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9
Q

bronchodilation

A

– Caused by sympathetic activation
– Enlarges diameter of airway
– Reduces resistance to airflow

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10
Q

bronchoconstriction

A
  • Parasympathetic activation
    – Reduces diameter of airway
  • Histamine release (allergic reactions)
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11
Q

Alveolar cell layer

A
pneumocytes type I 
-thin walls 
-site of gas exchange 
-monitored by macrophages
pneumocytes type II 
-produces surfactant
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12
Q

surfactant

A

– Oily secretion
– phospholipids + proteins
– Coats alveolar surface and reduces surface tension

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13
Q

respiratory distress syndrome

A

– Alveoli collapse after each exhalation

– Caused by inadequate amounts of surfactant due to injury or genetic abnormalities

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14
Q

Pneumonia

A

– Inflammation of lung tissue
– Causes fluid to leak into alveoli
– Compromises function of blood air barrier

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15
Q

Gas exchange across blood air barrier is quick and efficient

A

– Because distance for diffusion is short

– And O2 and CO2 are small and lipid soluble

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16
Q

Blood pressure in pulmonary circuit

A

– Lower than that in systemic circuit

– Pulmonary vessels are blocked by blood clots, fat, or air bubbles

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17
Q

pulmonary embolism

A

A blocked branch of pulmonary artery that stops

blood flow to lobules or alveoli

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18
Q

external respiration

A

exchange of O2 and CO2 with external environment

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19
Q

internal respiration

A
  • Uptake of O2 and release of CO2 by cells

* Result of cellular respiration

20
Q

hypoxia

A

Low tissue oxygen levels

21
Q

anoxia

A

Complete lack of oxygen in tissues

22
Q

inhalation

A

inspiration

23
Q

exhalation

A

expiration

24
Q

the lower the pressure

A

the lower the diffusion

25
Q

resistance

A

bronchodilation and bronchoconstriction

26
Q

compliance

factors that affect compliance?

A

– A measure of expandability
– Lower compliance requires greater force to fill lungs

– Factors that affect compliance
• Connective tissue of lungs
• Level of surfactant production
• Mobility of thoracic cage

27
Q

at sea level the partial pressure is

A

760 mm Hg

28
Q

the other atoms (partial pressure)

A

N- 78%
0- 21%
water vapor - 0.5%
CO2- 0.04%

29
Q

solubility of gases in body fluid

A

– CO2 is highly soluble
– O2 is somewhat less soluble
– N2 has very limited solubility

30
Q

Partial pressures in plasma of pulmonary vein

A

– PCO2 =40mmHg
– PO2 =100mmHg
– PN2 =573mmHg

31
Q

Blood arriving in pulmonary arteries has

A
  • Low PO2

* High PCO2

32
Q

concentration gradient causes

A
  • O2 to enter blood

* CO2 to leave blood

33
Q

internal respiration what happens?

A

– Oxygenated blood mixes with deoxygenated blood

– Lowers PO2 of blood entering systemic circuit to about 95 mm Hg

34
Q

interstitial fluid

A

• PO2 40mmHg,PCO2 45mmHg

35
Q

Concentration gradient in peripheral capillaries is opposite of lungs

A

• CO2 diffuses into blood, O2 diffuses out of blood

36
Q

red blood cells have a higher affinity for

A

O and CO2

37
Q

O2 binds to ??? in hemoglobin (Hb) molecules

A

iron ions
• In a reversible reaction
• Forming oxyhemoglobin (HbO2)

38
Q

1 RBC has

1 Hb molecule binds

A

280 million Hb molecules

4 oxygen molecules

39
Q

hemoglobin saturation

A

% heme units containing bound oxygen at any given moment

40
Q

factors affecting Hb saturation

A

– PO2 of blood
– Blood pH
– Temperature
– Metabolic activity within RBCs

41
Q

When temperature increases, hemoglobin

When temperature decreases, hemoglobin

A

releases more oxygen

holds oxygen more tightly

42
Q

the more BPG released

A

more oxygen released

• Due to increase in pH or certain hormones

43
Q

fetal hemoglobin

A

higher affinity for hemoglobin

• binds more O2 than does adult Hb, takes O2 from maternal blood

44
Q

70% of co2 in solution transported as

23% is

A

bicarbonate ions (HCO3-)

bound to protein portions of Hb molecules
in RBCs
• Forming carbaminohemoglobin

45
Q

baroreceptors

A

in aortic or carotid sinuses sensitive to changes in blood pressure

46
Q

aging

A

elastic tissue deteriorates in lungs

47
Q

Emphysema

A
  • Affects individuals over age 50

- exposure to respiratory irritants (cigarette smoke)