Chapter 21 Flashcards
What is the chemical name of a drug?
The first name when a drug is developed - identifies the actual chemical structure
What is the generic name of a drug?
Name given when the drug becomes commercially available - simpler name derived from the chemical name
What is another name for generic name?
Nonproprietary name
What is a trade name/brand name?
Names given to drugs to specify that drug is made by a specific company
Examples of trade names?
Motrin and Advil
What are other ways to classify drugs?
By action or legal classification
Drugs that are grouped together because they relieve pain are called:
Analgesics
How are drugs classified according to the law?
Prescription and non-prescription
What are examples of non-prescription drugs?
Vitamins, dietary supplements
What is the most common dosage form?
Tablet
Characteristics of tablets
Can be enteric coated or scored
Some may be extended release
Characteristics of capsules
Can be powdered or liquid drug contained in a gelatin shell
What is inhalation dosage used for?
Local or systemic effects
Local - Asthema or COPD
Systemic - General anesthesia
Characteristics of a solution dosage?
One or more drugs dissolved on liquid carrier.
Rapidly absorbed
Administered orally or parenterally
Characteristics of suspension dosage?
One or more drugs in small particles are suspended in liquid carrier
Not water soluble - should be shaken before administered
Should not be administered intravenously
Characteristics of Transdermal patch?
Applied to skin surface and absorbed into the blood stream
Releases drug over time
Metals in patch can overheat in MRI
Can a patient be prescribed 2 different action classification of drugs for same symptom?
Yes.
What are analgesics?
Drugs that releive pain without causing loss of consiousness
What are the two categories of Analgesics?
Opioids (narcotic)
Non-opioids (non-narctoric)
What are examples of Opioids and their side effects?
Morphine and Demerol
Nausea, vomitting, consitipation
Possible physiological dependency
What are examples of Non-opioids?
Tylenol
Relationship between opioids and addiction
Addiction is not common with long term opioid use
What are anesthetics?
Act on the CNC to produce a loss of sensation
Two types of anesthetics?
General and Local
Examples of general anesthetics?
Ether
Pentothal
How does local anesthetic work?
Block nerve conduction to that part of the body
Examples of local anesthetics?
Novocain, lidocaine
How is general anesthetics administered?
Inhalation or IV
When is general anesthetics used?
Major surgery
Side effects of local anesthetic?
Irregular heartbeat, difficulty breathing or death
How do anti-anxiety medications work?
Act on CNS to clam patient
What are examples of anti-anxiety agents?
Valium and Ativan
Versed - pre-op drug
Xanax
What are antiarrhythymics?
Used to treat heart arrythmias
What is an example of an antiarrhythymic?
Cordorone
What are antibiotics used for?
To destory or inhbit growth of microorganisms
What are the two kinds of antibiotics?
Broad spectrum
Narrow spectrum
What is broad spectrum effective against?
Large number of microorganisms
What is narrow spectrum effective against?
Small number of microorganisms
What is an example of board spectrum antibiotics?
Z-pak, Cirpo
What is an example of narrow spectrum antibiotics?
Penicillin and Erythromyacin
How do Anticholinergic (anti-spasmatic) agents work?
Reduce smooth muscle tone, motility of GI tract, and secretions of respiratory tract secretory glands
Side effects of anticholinergics?
Dry mouth
Rapid heartbeat
Delirium
What are examples of anticholinergics?
Atropine
When is Atropine used?
Pre-op to inhibit secretions and prevent bradycardia
What do anticoagulants do?
Slow down the coagulation time of blood (prevents blood clots)
What are anticoagulants used for?
Prevent thromboembolic disorders
Examples of anticoagulants?
Heparin
Coumadin
During what exam is Heparin used for?
Angiography, so catheter does not collect blood clots on it when placed in vessel
How is Heparin administered?
Invravenously - should not be intramuscular because it can cause a hematoma
What is Coumadin?
Oral anti-coagulant
Side effect of Heparin?
Too much can cause internal bleeding and hemorraging
What are anticonvulsants used for?
Drugs used to prevent or control seizures, either grand mal or petite
Examples of anticonvulsants?
Dilantin - grand mal
Depakote - petite
How long does it take for antidepressents to work?
6-12 weeks
Examples of antidepressants?
Prozac
Zoloft
Paxil
Lexapro
What is associated with depression?
Low serotonin levels
How does serotonin work?
Makes synapse of the nerves more smooth
What are SSRIs used for?
Panic disorders
Side effects of antidepressants?
Nausea and vomitting
What are the two types of diabetes?
Type 1 (diabetic mellitus)
Type 2
How are Diabetes type 1 and type 2 different?
Type 1 - absence of insulin
Type 2 - insulin deficiency and insulin resistance
How is Type 1 diabetes treated?
Insulin
Medicines for Type 2 diabetes?
Glyburide (micronanse)
Glipzide (glucotrol)
Metformin (glucophage or glucovane)
Pioglitzone (actos)
When should Metformin not be taken?
Prior to iodinated contrast studies - can cause renal failure
What are antiemetics?
Drugs used to prevent nausea and vomitting
Common antiemetics?
Compazine and Zofran
Function of antihistamines?
Treat both acute and chronic disorders
Two groups of antihistamines?
Sedating (first generation)
Non-sedating (second generation)
Example of sedating antihistamine:
Benadryl
Administered intramusculary, if emergency
Example of non-sedating antihistamine?
Claritin - taken orally for not as severe allergic reactions
Function of antihyperlipdemic agents?
Reduce lipid levels in blood steam which can lead to Atherosclerosis
What is the main group of antihyperlipdemics?
Statins
Two common statin drugs are:
Lipitor and Zocor
Side effects of statin drugs?
Constipation, abdominal pain, muscle pain, liver abnormalities
What should cholestorol levels be to take statins?
Less than 200
What is the leading cause of death in the US for both men and women?
Coronary Heart Disease caused by Atheroscerosis
What are antihypertensive agents used to treat?
Hypertension - high blood pressure
Examples of antihypertensive agents?
Tenormin (atenolol)
Lopressor (metopropol)
Vasotec (enalapril)
What are antiplatelets used for?
Inhibit platelet build up in blood steam
When are antiplatelets needed?
Myocardial infraction
Strokes
Trans Ischemic attack
What does Ischemia mean?
Not getting enough blood
Antiplatletes are often refered to as:
Blood thinners
Examples of blood thinners(antiplatelets)?
Aspirin
Plavix (clopidogrel)
Repro
Side effect of blood thinners?
Can cause bleeding
What are antiphychotics used for?
Treat psychiatric disorders
Adverse effects of antiphychotics?
Sedation and orthostatic hypotension
Example of antipsychotic?
Haloperidol (Haldol)
What are antiulcer agents used for?
Peptic ulcers - both gastro and duodenal and GERD
What is GERD?
Gastro Esophageal Reflux Disease
Reflux of acid from stomach into esophagus
What are peptic ulcers from?
Helicobacter Pylori
Common anti-ulcer drugs
Zantac
Prevacid
What are antivirals used for?
Inhibit or supress growth of viruses (pathogens)
What are common viral infections?
Herpes Simplex
Chicken Pox
Shingles
Influenza
HIV
What are the common antiviral drugs used to treat HIV?
Retrovir
AZT
What are Bronchodilators used for?
Treatement of asthma and COPD
What are side effects of Bronchodilators?
Nervousness
Tachycardia
What is a common bronchodilator?
Albuterol
What are Cholinesterase inhibitors used for?
Alzheimer’s Disease
What do Cholinesterase inhibitors do?
Prevents too much uptake of acetylcholine - a major neurotransmitter
What do Coagulants do?
Control hemorrage or speed up coagulation
What are most Coagulants manufactured from?
Vitamin K
What are Corticosteroids used for?
Treat both long term chronic inflammation disorders and short term acute inflammatory disorders
What is a common Corticosteriod?
Flovent - Fluticasone
What are diuretics used for?
Increase the amount of urine being excreted by the kidneys
What is a common diuretic?
Furosemide (Lasix)
What is Lasix?
A diuretic used to treat fluid backup that may come from congestive heart failure
What are diuretics often used with?
Antihypertensive drugs
What are Emetics?
Drugs used to produce vomitting
What is a common Emetic?
Ipecac
What are hormone drugs used for?
To stimulate the functional activity of the hormonal system
What is a common HR drug that stimulates hormones?
Premarin
Common HR drugs that inhibit hormones?
Tamoxifen - estrogen inhibitor
What are mood stabilizing drugs used for?
Prevent mood swings
Treat bipolar disorder
What are NSAIDS used for?
Act as an analgesic
Fever reducer
Inflammation
Common NSAID?
Ibuprofen (Motrin)
What NSAID was on the news for causing CV issues?
Celebrex
What are sedatives used for?
Mild sedation to complete sleep
Side effect of sedatives?
Can lead to physical dependence
Common sedative?
Zolpidem (Ambien)
What are stimulants used for?
Increase function and/or activity of CNS and brain
Common stimulants for ADHD?
Ritalin and Adderall
Common stimulant found on crash cart?
Intropin - prevent shock and hypertension
What are Thrombolytics used for?
Dissolve clots (thrombi)
Common Thrombolytic?
Activase - adminstered parenterally for MI/stroke
What does Vasocontrictors do?
Cause blood vessels to constrict
Common vasoconstrictor?
Norepinephrine
What do Vasodilators do?
Cause blood vessels to dilate
What are Vasodilators used for?
Vasular disease and angina (heart pain)
Common vasodilator?
Nitroglycerin
Epineprhine