Chapter 20 - Antimicrobial Drugs [Reveresed] Flashcards
the use of chemical to treat a disease
chemotherapy
first scientist to use a chemical to treat disease (Syphilis)
Paul Ehrlich
substance that interferes with microbial growth
Antimicrobial agent
agent that affects a small group of microbes
Narrow-Spectrum Drugs
agent that affects a wide variety of microbes
Broad-Spectrum Drugs
Selective toxicity, spectrum of action, effective doses, delivery/effective penetration and retention are all _____
Criteria for ideal microbial drug
Antibacterial drugs target _______
Bacteria
Antimycobacterial drugs target _______
Genus Mycobacterium
Antimycotic drug target _______
Fungi
Antiviral drug target _______
Viruses
Anti-retroviral drugs target __________
Retroviridae family
Antimalarial/antiprotozoal drugs target _______
Genus Plasmodium
Anthelminthic drugs target ______
parasites that are worms
Name the type of drug, family and mechanism of action:
Natural and Narrow spectrum drugs derived from fungus
Drug type: Antibacterial
Family: Penicillin
MOA: Inhibition of peptidoglycan synthesis
misc. (Natural PCN)
Name the type of drug, family and mechanism of action:
Semisynthetic components
Drug type: Antibacterial
Family: Penicillin
MOA: Inhibition of peptidoglycan synthesis
misc. (Semisynthetic PCN)
Name the type of drug, family and mechanism of action:
Natural & synthetic components and resistant to penicillinase
Drug type: Antibacterial
Family: Penicillin
MOA: Inhibition of peptidoglycan synthesis
misc. (Semisynthetic PCN)
Name the type of drug, family and mechanism of action:
Narrow spectrum drug that is effective towards gram (+) bacteria
Drug type: Antibacterial
Family: Penicillin
MOA: Inhibition of peptidoglycan synthesis
misc. (Natural PCN)
Name the type of drug, family and mechanism of action:
Broad spectrum drug derived from fungus
Drug type: Antibacterial
Family: Cephalosporin
MOA: Inhibition of peptidoglycan synthesis
Name the type of drug, family and mechanism of action:
Penicillinase-resistant and classified into generations
Drug type: Antibacterial
Family: Cephalosporin
MOA: Inhibition of peptidoglycan synthesis
Name the type of drug, family and mechanism of action:
Topical application for ABX-resistant MRSA
Drug type: Antibacterial
Family: Polypeptide
MOA: Inhibition of peptidoglycan synthesis