Chapter 2 (Pt. 2) Flashcards
the _______ is a dense region in the nucleus, associated with ribosomal subunit assembly
nucleolus
is the nucleolus an organelle?
no. not membrane bound
ribosomal subunit is made up of what? (2)
- rRNA (ribosomal RNA)
- proteins
eukaryotic ribosomal subunits are made in the _____ and assembled in the ______
nucleus
cytosol
what do ribosomes do?
synthesis of proteins (translation)
structure of a eukaryotic vs. prokaryotic ribosome?
EU: 80S
PR: 70S
where are ribosomes found? (2)
freely in the cytosol or attached to the rough ER
which type of ribosomes tend to make proteins that function within the cytosol of the cell
free
ribosomes that bind to the rough ER will synthesize proteins that go where?
into the rough ER lumen
rough ER is continuous with the ?
ER lumen is continuous with the ?
outer nuclear membrane
perinuclear space
what happens to proteins inside the rough ER?
they are manipulated
what is a common manipulation for proteins in the rough ER?
glycosylation to make glycoproteins
what are the two fates of proteins that enter the lumen of the rough ER?
- become part of the cell membrane
- exocytosis
smooth/rough ER: synthesizes lipids and steroid hormones for export
smooth
smooth/rough ER: functions in the breakdown of toxins and drugs
smooth
smooth/rough ER: not covered by ribosomes
smooth
smooth ER is usually not attached to the
outer nuclear membrane
ERs send vesicles to the
cis-face of the Golgi
vesicles travel from the _____ to __________ of the Golgi (faces)
cis-face to trans-face
what is the main function of the Golgi apparatus?
directing molecules to their correct locations
which organelles break down nutrients/bacteria/cell debris?
lysosomes
lysosomes receive vesicles containing digestive enzymes from the ?
Golgia apparatus
intracellular breakdown of unneeded/defective cellular components is called
autophagy
lysosomes function in ______ when they release their contents into the cell
apoptosis