Chapter 2 (Pt. 1) Flashcards
what are the three main components in a cell membrane?
phospholipids
cholesterol
proteins
what is the structure of a phospholipid? (3)
- glycerol backbone
- two fatty acid tails
- hydrophilic phosphate group
what are the two classes of membrane proteins?
integral; peripheral
which proteins are embedded in the core of the plasma membrane?
integral
which proteins extend all the way through the membrane?
transmembrane
role of transmembrane proteins? (2)
- signaling
- transport large, polar molecules across the cell membrane
which proteins do not extend through the entire bilayer?
peripheral
what are the three types of peripheral proteins?
receptors
adhesion
recognition
recognition proteins, aka
glycoproteins
ligands that bind to a receptor protein and activate its response are called:
agonists
ligands that bind to a receptor and prevent it from activating are called:
antagonists
agonists vs. antagonists?
AGONIST: bind to a receptor protein and activate its response
ANTAGONISTS: bind to a receptor and prevent it from activating
what are the three main factors that affect membrane fluidity?
-temperature
-cholesterol
-phospholipid tail unsaturation
which particles can travel directly across the phospholipid bilayer via simple diffusion?
small, uncharged, nonpolar
saturated vs unsaturated fatty acids?
SATURATED: saturated with hydrogens at each carbon, straight.
UNSATURATED: double bonds, crooked.
osmosis is a type of _______
simple diffusion
give a definition and example of simple diffusion:
flow of substances down their concentration gradient; no energy.
osmosis.
how do large, hydrophilic molecules travel across the bilayer?
facilitated transport by transmembrane proteins?
what are the three main types (directions) of facilitated transport?
- uniport
- symport
- antiport
what two classes of transmembrane proteins are involved with facilitated transport?
channel; carrier