Chapter 19 Flashcards
45% of blood. Made up of platelets, WBCs, and RBCs
Formed elements
Made of water and proteins such as albumins, globulins, and fibrinogen. 55% of blood
Blood plasma
Platelets have a _______ life span of ___ to ____ days.
Short, 8 to 10
Hormone produced by the liver that stimulates the formation of platelets from megakaryocytes.
Thrombopoietin
Process by which the formed elements of blood develop.
Before birth, this occurs in sac of embryo. But red bone marrow becomes the primary site.
Hematopoiesis
Increases the number of red blood cell precursors. Produced primarily by cells in kidneys. If kidneys fail, RBC production is inadequate. Bad hematocrit-> no O2 to body tissues.
Erythropoietin
Store, accumulate, and pass along o2 very well. Floppiness allows them to flow through capillaries.
Don’t have nucleus, can’t produce proteins, not really living cells, die in abt 120 days. 4-6 mil per microliter
Red blood cells
Immature RBCs. Low count indicates low erythropoietin rate. Elevated rate vise versa. As the cell matures, the nucleus disappears, and amt of hemoglobin increases.
Reticulocytes
This is packed inside RBC. Carries o2 and co2. Each RBC contains 280 mil molecules of hgb
Hemoglobin
Excess RBCs
Polycythemia
Weird shaped cells by beta globins
Super bad…
Sickle cell anemia
Loss of lots of blood can lead to this
Hemorrhagic anemia
Insufficient RBCs, or hemoglobin
Anemia
WBC that fights bacterial infection. Is active in phagocytosis.
Neutrophil
WBCs that increase during parasitic infection.
Eosinophils
WBCs present in histamine reactions. Big role in inflammatory response.
Basophils
Not granulocytes. They are phagocytes.
Monocytes
WBCs that aren’t granulocytes. Increase in acute viral infections. Responders to specific foreign antigens. Nucleus takes up whole cell.
Lymphocytes
Process that stops bleeding
Hemostasis
Occurs as damaged blood vessels constrict.first stage of hemostasis
Vascular spasm
Platelets adhere to endotherm that’s damaged. Second stage of hemostasis.
Form platelet plug
Blood clot. 3rd stage of hemostasis
Coagulation
2 pathways to coagulation cascade
Intrinsic and extrinsic
Clotting in an unbroken blood vessel
Thrombosis